Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 4/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CENPE | Q02224 | 4/20 | 0.33 |
| ▸ | ESRRG | P62508 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580209 | 0.92 | MCHR1 (0.40) | BTKHDAC3HDAC8HDAC6MELK | |
| SCHEMBL3574285 | 0.89 | ESRRG (0.36) | CENPEESRRGTP53MAPTNR1H4 | |
| SCHEMBL3583608 | 0.87 | ESRRG (0.35) | CENPEESRRGTP53MAPTNR1H4 | |
| SCHEMBL3583661 | 0.87 | BTK (0.41) | BTKHDAC3HDAC8HDAC6CRHR1 | |
| SCHEMBL9958256 | 0.85 | NR1H4 (0.38) | THRBCENPEESRRGTP53MAPT | |
| SCHEMBL3579944 | 0.84 | MCHR1 (0.39) | GPR6CRHR1OPRM1OPRD1 | |
| SCHEMBL3586536 | 0.82 | MCHR1 (0.37) | BTKHDAC3HDAC8HDAC6CRHR1 | |
| SCHEMBL3572867 | 0.80 | MEN1 (0.38) | HDAC3HDAC8HDAC6ESRRGNR1H4 | |
| SCHEMBL3576692 | 0.80 | ESRRG (0.37) | ESRRGNR1H4OPRM1OPRD1ESRRB | |
| SCHEMBL3580374 | 0.79 | ESRRG (0.36) | HDAC3HDAC8HDAC6ESRRGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |