Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574247 | 0.79 | DCPS (0.51) | TGFBR1EGFRKDM4EALDH1A1HPGD | |
| SCHEMBL8351780 | 0.79 | KDM4E (0.47) | TGFBR1EGFRKDM4EALDH1A1HPGD | |
| SCHEMBL11729820 | 0.79 | TGFBR1 (0.48) | TGFBR1EGFRKDM4EALDH1A1HPGD | |
| SCHEMBL3272699 | 0.77 | MEN1 (0.38) | EGFRNQO2GAKPDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL3574160 | 0.77 | DCPS (0.50) | TGFBR1EGFRKDM4EALDH1A1HPGD | |
| SCHEMBL18378884 | 0.76 | TGFBR1 (0.45) | TGFBR1KDM4EALDH1A1HPGDDCPS | |
| SCHEMBL24891144 | 0.76 | ELANE (0.44) | ALDH1A1ELANE | |
| SCHEMBL8781926 | 0.75 | DCPS (0.47) | TGFBR1KDM4EALDH1A1HPGDDCPS | |
| SCHEMBL8781923 | 0.75 | TGFBR1 (0.43) | TGFBR1EGFRKDM4EALDH1A1HPGD | |
| SCHEMBL26317662 | 0.75 | TGFBR1 (0.45) | TGFBR1KDM4EALDH1A1HPGDDCPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | disclosed |
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | disclosed |
| US-20060189604-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
| EP-1537123-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004002992-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189604-A1 | Compounds | ELANE, PIGS, SDHA | TGFBR1 3221/4885EGFR 2727/4885KDM4E 3723/4885 |
| US-20100081650-A1 | Antimicrobial Compounds | ELANE, NISCH, PIGS | TGFBR1 4318/4885EGFR 4166/4885KDM4E 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.