SCHEMBL3583719

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29225207	0.85	PKM (0.53)	PKMCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL8182308	0.83	GABRA1 (0.53)	TSHR
	SCHEMBL16675476	0.81	MAPK1 (0.49)	PKMCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL6284340	0.80	PKM (0.53)	PKMCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL15245643	0.80	PKM (0.54)	PKMCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL14495565	0.80	PKM (0.50)	PKMCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL4255993	0.79	MAPK1 (0.50)	CYP1A2CYP3A4CYP2C9CYP2C19SMN1; SMN2
	SCHEMBL30032189	0.76	TSHR (0.50)	MAPTKDM4ETSHRPOLBNPSR1
	SCHEMBL14495545	0.76	PKM (0.46)	PKMCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL3604125	0.76	NR3C1 (0.48)	MAPTKDM4ETSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.