Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.48 |
| ▸ | PGR | P06401 | 9/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.48 |
| ▸ | AR | P10275 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600074 | 0.88 | LMNA (0.47) | TSHRHSD17B10MAPK1MAPTNPSR1 | |
| SCHEMBL3591270 | 0.79 | GLA (0.47) | PGRNR3C2KDM4ETSHRHSD17B10 | |
| SCHEMBL3583719 | 0.76 | PKM (0.50) | KDM4ETSHRMAPTNPSR1 | |
| SCHEMBL3596257 | 0.75 | GLA (0.39) | NR3C1NR3C2KDM4ETSHRHSD17B10 | |
| SCHEMBL6089321 | 0.74 | NR3C1 (0.54) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6090093 | 0.72 | NR3C2 (0.56) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL6092867 | 0.71 | NR3C2 (0.54) | NR3C1PGRNR3C2ARKDM4E | |
| SCHEMBL6091273 | 0.71 | NR3C2 (0.54) | NR3C1PGRNR3C2ARKDM4E | |
| SCHEMBL6090080 | 0.71 | NR3C1 (0.49) | NR3C1PGRNR3C2ARPLA2G7 | |
| SCHEMBL7949051 | 0.71 | NR3C1 (0.44) | NR3C1PGRNR3C2ARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | NR3C1, NR3C2, NR0B1 | NR3C1 1/4885PGR 325/4885NR3C2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.