SCHEMBL3584002

SCHEMBL3584002

CC(C)(C)OC(=O)NCCC(N)C(=O)NCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.50
IDO1 P14902 1/20 0.49
CA1 P00915 3/20 0.48
CA2 P00918 2/20 0.48
CA12 O43570 1/20 0.48
CA7 P43166 1/20 0.48
CA14 Q9ULX7 1/20 0.48
ATM Q13315 1/20 0.47
CTSS P25774 3/20 0.46
BACE1 P56817 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
GAA P10253 1/20 0.45
SYK P43405 1/20 0.45
KCNA5 P22460 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2921238 1.00 CTSK (0.50) CTSKIDO1CA1CA2CA12
SCHEMBL2931394 0.93 MEN1 (0.52) CTSKIDO1CA1CA2CA12
SCHEMBL12340141 0.89 CTSS (0.57) CTSKCA1CA2ATMCTSS
SCHEMBL26268412 0.87 ATM (0.52) CTSKIDO1CA1CA2CA12
SCHEMBL13482390 0.87 L3MBTL1 (0.50) CA1CA2CA12CA7CA14
SCHEMBL14485300 0.85 ATM (0.53) CTSKCA1CA2CA12CA7
SCHEMBL14485298 0.85 ATM (0.53) CTSKCA1CA2CA12CA7
SCHEMBL2251347 0.84 CA2 (0.46) CTSKCA1CA2CA12CA7
SCHEMBL3177936 0.84 IDO1 (0.50) CTSKIDO1CA1CA12CA7
SCHEMBL12356362 0.84 CA2 (0.46) CTSKCA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 CTSK 2124/4885IDO1 1915/4885CA1 2542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.