SCHEMBL3584004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15459627	0.92	RET (0.49)	RETPGK1ADKWNT3ACKS1B
	SCHEMBL3576475	0.82	CNR2 (0.38)	RET
	SCHEMBL15453292	0.82	SLC6A7 (0.36)	RET
	SCHEMBL3471876	0.78	RXRA (0.53)	RETPGK1ADKCKS1BSKP1
	SCHEMBL13437644	0.75	JAK2 (0.47)	CKS1BSKP1SKP2
	SCHEMBL6787575	0.73	ADK (0.63)	RETPGK1ADKWNT3ACKS1B
	SCHEMBL15459629	0.73	RET (0.42)	RET
	SCHEMBL1904170	0.71	ADK (0.59)	RETPGK1ADKCKS1BSKP1
	SCHEMBL30893596	0.71	ADK (0.59)	RETPGK1ADKCKS1BSKP1
	SCHEMBL16661039	0.71	RET (0.51)	RETPGK1ADKWNT3ACKS1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.