SCHEMBL358439

SCHEMBL358439

c1ccc(Oc2nc3ccccc3o2)cc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.56
KCNH2 Q12809 1/20 0.55
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CTSD P07339 1/20 0.46
MAPT P10636 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CNR2 P34972 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818654 0.94 LTA4H (0.61) LTA4HKCNH2CTSDMAPTNPC1
SCHEMBL9499089 0.88 NPC1 (0.52) LTA4HKCNH2MAPTNPC1RAB9A
SCHEMBL29818612 0.86 LTA4H (0.54) LTA4HKCNH2CTSDMAPTNPC1
SCHEMBL28437684 0.86 LTA4H (0.54) LTA4HKCNH2CTSDMAPTNPC1
SCHEMBL28437938 0.86 LTA4H (0.54) LTA4HKCNH2TDP1L3MBTL1CTSD
SCHEMBL28435756 0.86 LTA4H (0.54) LTA4HKCNH2TDP1L3MBTL1CTSD
SCHEMBL8688782 0.86 LTA4H (0.54) LTA4HKCNH2CTSDMAPTNPC1
SCHEMBL8688786 0.86 LTA4H (0.54) LTA4HKCNH2MAPK1CTSDMAPT
SCHEMBL14542334 0.86 LTA4H (0.54) LTA4HKCNH2MAPK1CTSDMAPT
SCHEMBL29818690 0.86 LTA4H (0.54) LTA4HKCNH2TDP1L3MBTL1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 716 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12635409-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-05-19 US disclosed
US-12615957-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-04-28 US disclosed
EP-3968404-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2026-04-01 EP disclosed
US-20260090262-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-03-26 US disclosed
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 EP disclosed
US-12527214-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-13 US disclosed
EP-4167707-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2025-12-10 EP disclosed
US-20250359473-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERAL DISPLAY CORPORATION (US) 2025-11-20 US disclosed
EP-0907650-B1 N- 4-(HETEROARYLMETHYL)PHENYL]-HETEROARYLAMINES JANSSEN PHARMACEUTICA NV (BE) 2002-12-04 EP disclosed
US-6486187-B1 N-[4-(heteroarylmethyl)phenyl]-heteroarylamines JANSSEN PHARMACEUTICA N.V. (BE) 2002-11-26 US disclosed
WO-2001087828-A1 N-SUBSTITUTED PEPTIDYL NITRILES AS CYSTEINE CATHEPSIN INHIBITORS NOVARTIS AG (CH) 2001-11-22 WO disclosed
US-6124330-A A RETINOIC MIMETIC COMPOUND FOR TREATING A WARM-BLOODED ANIMAL SUFFERING FROM A DISEASE BY AN ABNORMAL PROLIFERATION AND/OR ABNORMAL DIFFERENTIATION OF NORMAL, PRENEOPLASTIC OR NEOPLASTIC CELLS JANSSEN-CILAG S.A. (FR) 2000-09-26 US disclosed
EP-0907650-A1 N- 4-(HETEROARYLMETHYL)PHENYL]-HETEROARYLAMINES JANSSEN PHARMACEUTICA N.V. (BE) 1999-04-14 EP disclosed
WO-1997049704-A1 N-[4-(HETEROARYLMETHYL)PHENYL]-HETEROARYLAMINES JANSSEN PHARMACEUTICA N.V. (BE) 1997-12-31 WO disclosed
US-4888041-A POST EMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-12-19 US disclosed
EP-0245804-A3 HERBICIDALLY ACTIVE SUBSTITUTED PHENOXY BENZOXAZOLE (OR BENZOTHIAZOLE) COMPOUNDS PPG INDUSTRIES, INC. (US) 1988-06-08 EP disclosed
US-4746351-A POSTEMERGENCE PPG INDUSTRIES, INC. (US) 1988-05-24 US disclosed
EP-0245804-A2 Herbicidally active substituted phenoxy benzoxazole (or benzothiazole) compounds PPG INDUSTRIES, INC. (US) 1987-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12615957-B2 Organic electroluminescent materials and devices LBR, NR4A1, MLX LTA4H 2072/4885KCNH2 1131/4885MAPK1 2128/4885
US-12635409-B2 Organic electroluminescent materials and devices NSUN2, CTNND1, NSD1 LTA4H 865/4885KCNH2 28/4885MAPK1 2667/4885
US-20260090262-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TLL1, TLL2, LAS1L LTA4H 1043/4885KCNH2 224/4885MAPK1 1951/4885
US-20250359473-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP LTA4H 2372/4885KCNH2 599/4885MAPK1 3880/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 LTA4H 4508/4885KCNH2 369/4885MAPK1 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.