Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23048845 | 0.86 | ADRA2C (0.57) | ADRA2CHTR3AAGXTALDH1A1HDAC3 | |
| SCHEMBL23916588 | 0.86 | ADRA2C (0.61) | ADRA2CHTR3AAGXTALDH1A1HDAC3 | |
| SCHEMBL1444185 | 0.84 | ALDH1A1 (0.64) | ADRA2CHTR3AAGXTALDH1A1HDAC3 | |
| SCHEMBL29442412 | 0.84 | ALDH1A1 (0.64) | ADRA2CHTR3AAGXTALDH1A1HDAC3 | |
| SCHEMBL1559226 | 0.78 | ADRA2C (0.65) | ADRA2CHTR3AAGXTALDH1A1HDAC3 | |
| SCHEMBL28199225 | 0.78 | ADRA2C (0.46) | ADRA2CALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL26423291 | 0.78 | ADRA2C (0.65) | ADRA2CHTR3AAGXTALDH1A1HDAC3 | |
| SCHEMBL3593153 | 0.77 | ALDH1A1 (0.69) | ADRA2CHTR3AALDH1A1HDAC3HDAC4 | |
| SCHEMBL30468954 | 0.76 | ADRA2C (0.62) | ADRA2CHTR3AAGXTALDH1A1HDAC3 | |
| SCHEMBL29053019 | 0.76 | ADRA2C (0.62) | ADRA2CHTR3AAGXTALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448802-B | Acrylamide derivative as histone deacetylase inhibitors for cancer treatment | DAC SRL | 2012-11-07 | — | — | CN | disclosed |
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | ADRA2C 3317/4885HTR3A 3666/4885AGXT 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.