SCHEMBL26423291

SCHEMBL26423291

CN1CCN(c2cccc(S)c2)CC1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 2/20 0.65
HTR3A P46098 1/20 0.53
AGXT P21549 1/20 0.53
GAA P10253 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPT P10636 2/20 0.47
PTK2B Q14289 2/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
RECQL P46063 1/20 0.47
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
GLA P06280 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GFER P55789 1/20 0.46
ESR2 Q92731 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PLOD2 O00469 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30468954 0.98 ADRA2C (0.62) ADRA2CHTR3AAGXTGAAKDM4E
SCHEMBL29053019 0.98 ADRA2C (0.62) ADRA2CHTR3AAGXTGAAKDM4E
SCHEMBL6635208 0.82 MEN1 (0.52) ADRA2CHTR3AAGXTGAAKDM4E
SCHEMBL7924167 0.78 KCNH2 (0.67) ADRA2CHTR3AAGXTKDM4EMAPT
SCHEMBL448110 0.78 ADRA2C (1.00) ADRA2CHTR3AAGXTGAAKDM4E
SCHEMBL3584889 0.78 ADRA2C (0.61) ADRA2CHTR3AAGXTGAAKDM4E
SCHEMBL1039861 0.77 DRD2 (0.68) ADRA2CHTR3AAGXTMAPTKMT2A
SCHEMBL22547277 0.77 ADRA2C (0.65) ADRA2CHTR3AAGXTGAAKDM4E
SCHEMBL487317 0.77 LMNA (0.59) AGXTKDM4EMAPTMAPK1HTT
SCHEMBL1384498 0.77 KCNH2 (0.65) ADRA2CHTR3AGAAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023191533-A1 THIOBENZIMIDAZOLE DERIVATIVE PREPARATION METHOD AND NOVEL INTERMEDIATE THEREFOR 고려대학교 산학협력단 2023-10-05 WO disclosed