SCHEMBL3585234

SCHEMBL3585234

CN1[CH]C=Cc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
P2RX4 Q99571 8/20 0.37
MAOA P21397 1/20 0.37
HTR1A P08908 3/20 0.37
DRD2 P14416 3/20 0.37
HTR2A P28223 3/20 0.37
SLC6A4 P31645 3/20 0.37
HRH1 P35367 3/20 0.37
HTR6 P50406 2/20 0.37
HTR7 P34969 1/20 0.37
MAPK1 P28482 3/20 0.36
LMNA P02545 2/20 0.36
TSHR P16473 1/20 0.36
SCN4A P35499 1/20 0.36
SCN5A Q14524 1/20 0.36
SCN9A Q15858 1/20 0.36
P2RX1 P51575 4/20 0.36
P2RX3 P56373 4/20 0.36
P2RX7 Q99572 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1249107 0.80 MTNR1A (0.39) MTNR1AMTNR1BP2RX4MAOAHTR1A
SCHEMBL2607158 0.75 MAPT (0.49) MTNR1AMTNR1BP2RX4MAOAHTR1A
SCHEMBL5375186 0.73 LMNA (0.41) MTNR1AMTNR1BP2RX4MAPK1LMNA
SCHEMBL4966227 0.71 HSD17B3 (0.38) MAPK1LMNATSHRADRA1ASLC6A3
SCHEMBL4962293 0.69 MCL1 (0.33) LMNATSHRALDH1A1
SCHEMBL28270709 0.68 MTNR1A (0.37) MTNR1AMTNR1BP2RX4HTR1ADRD2
SCHEMBL7061846 0.68 P2RX4 (0.34) MTNR1AMTNR1BP2RX4HTR1ADRD2
SCHEMBL6307592 0.67 MAPT (0.36) MTNR1AMTNR1BP2RX4MAOAMAPK1
SCHEMBL8402837 0.67 MTNR1A (0.54) MTNR1AMTNR1BP2RX4HTR1ADRD2
SCHEMBL17187258 0.65 MAOA (0.48) MAOAHTR2ASLC6A4HRH1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115884773-A Pharmaceutical preparation 詹森药业有限公司 2023-03-31 CN disclosed
EP-3140306-B1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENT INC (US) 2021-11-17 EP disclosed
US-20210026054-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC INC. 2021-01-28 US disclosed
US-20180259693-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2018-09-13 US disclosed
US-20170235034-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2017-08-17 US disclosed
US-9683102-B2 Photo-stable and thermally-stable dye compounds for selective blue light filtered optic FRONTIER SCIENTIFIC, INC. (US) 2017-06-20 US disclosed
EP-3140306-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC Frontier Scientific, Inc. (US) 2017-03-15 EP disclosed
EP-2104670-B3 NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS ADDEX PHARMACEUTICALS SA (CH) 2016-09-21 EP disclosed
EP-2104670-B1 NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS ADDEX PHARMACEUTICALS SA (CH) 2016-02-17 EP disclosed
WO-2015171507-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2015-11-12 WO disclosed
US-5434265-A Inhibitors of HIV protease ELI LILLY AND COMPANY (US) 1995-07-18 US disclosed
WO-1995014017-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1995-05-26 WO disclosed
EP-0652009-A1 Identification and use of protease inhibitors ELI LILLY AND COMPANY (US) 1995-05-10 EP disclosed
WO-1995009843-A1 HIV PROTEASE INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1995-04-13 WO disclosed
EP-0609625-A1 Inhibitors of HIV protease useful for the treatment of AIDS ELI LILLY AND COMPANY (US) 1994-08-10 EP disclosed
EP-0604184-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604182-A2 Inhibitors of HIV protease useful for the treatment of Aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604186-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604185-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604183-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed