Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | AGXT | P21549 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645074 | 1.00 | ACHE (0.44) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL758088 | 1.00 | ACHE (0.44) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL22106133 | 0.78 | PARP10 (0.54) | ALDH1A1AGXT | |
| SCHEMBL563967 | 0.77 | ACHE (0.50) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL235851 | 0.77 | ACHE (0.50) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL4401131 | 0.77 | ACHE (0.50) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL12903527 | 0.74 | MEN1 (0.47) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL254471 | 0.74 | ACHE (0.47) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL280535 | 0.74 | ACHE (0.47) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL1094237 | 0.74 | ACHE (0.47) | ACHETDP1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865859-A | Preparation method of enantiomerically pure p-toluenesulfonamide | 常州琦诺生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| WO-2023227996-A1 | A DEUTERATED AMINE COMPOUNDS AND PROCESS FOR SYNTHESIS THEREOF | CLEARSYNTH LABS LIMITED (IN) | 2023-11-30 | — | — | WO | claimed |
| CN-116924974-A | Preparation method of fluopicolide | 天津均凯农业科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-113620769-B | Preparation method of terpinolene | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-108963389-B | Gelable system for lithium-air battery and preparation method and application thereof | 北京师范大学 | 2020-11-13 | — | — | CN | claimed |
| CN-108440349-B | Preparation method of chiral optical pure p-toluenesulfinamide | 上海李氏化学科技有限公司 | 2020-10-20 | — | — | CN | claimed |
| CN-108558714-B | Preparation method of chiral optical pure p-toluenesulfinamide | 上海李氏化学科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-108484455-B | Method for synthesizing chiral optical pure p-toluenesulfinamide | 浙江凯普化工有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-108558714-A | A kind of chirality optical voidness is to the preparation method of toluenesulfinamide | 上海晋鲁医药科技有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-108484455-A | A kind of method of synthesis of chiral optical voidness to toluenesulfinamide | 上海晋鲁医药科技有限公司 | 2018-09-04 | — | — | CN | claimed |
| US-7476762-B2 | Methods for preparing sulfonamide compounds | WYETH (US) | 2009-01-13 | — | — | US | claimed |
| US-20070293680-A1 | For the preparation of (R)-(+)-6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl) methyl]-4-(3-chlorophenyl)-1-methyl2(1H)-quinolinone; farnesyl tranferase inhibitory activity | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-12-20 | — | — | US | claimed |
| US-20070254929-A1 | Fluoro-and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof | WYETH (US) | 2007-11-01 | — | — | US | claimed |
| US-20070249723-A1 | Methods for preparing sulfonamide compounds | WYETH (US) | 2007-10-25 | — | — | US | claimed |
| EP-1756085-A1 | DIASTEREOSELECTIVE SYNTHESIS PROCESS WITH 6-BROMO-4-(3-CHLOROPHENYL)-2-METHOXY-QUINOLINE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-28 | — | — | EP | claimed |
| EP-1608638-A1 | FLUORO-AND TRIFLUOROALKYL-CONTAINING HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION AND DERIVATIVES THEREOF | Wyeth (US) | 2005-12-28 | — | — | EP | claimed |
| WO-2005105783-A1 | DIASTEREOSELECTIVE SYNTHESIS PROCESS WITH 6-BROMO-4-(3-CHLOROPHENYL)-2-METHOXY-QUINOLINE | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-10 | — | — | WO | claimed |
| WO-2004092155-A1 | FLUORO-AND TRIFLUOROALKYL-CONTAINING HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION AND DERIVATIVES THEREOF | WYETH (US) | 2004-10-28 | — | — | WO | claimed |
| US-20040198778-A1 | Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof | WYETH | 2004-10-07 | — | — | US | claimed |
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254929-A1 | Fluoro-and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof | SCN8A, CHD8, CHRNA7 | ACHE 806/4885TDP1 3059/4885CA1 707/4885 |
| US-20070249723-A1 | Methods for preparing sulfonamide compounds | PNISR, RRM1, MRPS27 | ACHE 2489/4885TDP1 3155/4885CA1 2520/4885 |
| US-20040198778-A1 | Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof | BACE1, APP, PSEN1 | ACHE 501/4885TDP1 722/4885CA1 298/4885 |
| US-20070293680-A1 | For the preparation of (R)-(+)-6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl) methyl]-4-(3-chlorophenyl)-1-methyl2(1H)-quinolinone; farnesyl tranferase inhibitory activity | FNTB, CYP4F2, FNTA | ACHE 2039/4885TDP1 3429/4885CA1 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.