⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15895190 | 0.83 | — | — | |
| SCHEMBL22031726 | 0.81 | RXRA (0.35) | — | |
| SCHEMBL19831178 | 0.81 | RXRA (0.35) | — | |
| SCHEMBL3577162 | 0.81 | — | — | |
| SCHEMBL26988467 | 0.80 | TRPA1 (0.33) | — | |
| SCHEMBL29596980 | 0.77 | TLR7 (0.33) | — | |
| SCHEMBL487408 | 0.77 | TLR7 (0.33) | — | |
| SCHEMBL487400 | 0.76 | NTRK1 (0.33) | — | |
| SCHEMBL28754352 | 0.75 | GABRP (0.43) | — | |
| SCHEMBL487536 | 0.74 | CHRNB2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285873-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| EP-2004636-B1 | Substituted enaminocarbonyl compounds used as insecticides | BAYER IP GMBH (DE) | 2015-04-22 | — | — | EP | disclosed |
| US-8084452-B2 | Substituted enaminocarbonyl compounds used as insecticides | BAYER CROPSCIENCE AG (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20100240705-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| EP-2004636-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES | Bayer CropScience AG (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007115646-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |