SCHEMBL358634

SCHEMBL358634

Cc1cc(N(Cc2ccccc2)Cc2ccccc2)ccc1/C=N/N(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.55
GAA P10253 2/20 0.55
HTT P42858 2/20 0.55
MAPK1 P28482 2/20 0.55
CYP2C19 P33261 1/20 0.46
POLB P06746 2/20 0.44
EIF4H Q15056 1/20 0.44
ALDH1A1 P00352 5/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
KDM4E B2RXH2 3/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
MCL1 Q07820 1/20 0.40
NR3C1 P04150 1/20 0.39
SLC16A3 O15427 1/20 0.39
SLC16A1 P53985 1/20 0.39
G6PC1 P35575 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358635 1.00 MAPT (0.55) MAPTGAAHTTMAPK1CYP2C19
SCHEMBL8171068 0.88 MEN1 (0.46) MAPTGAAHTTMAPK1CYP2C19
SCHEMBL8171069 0.88 MEN1 (0.46) MAPTGAAHTTMAPK1CYP2C19
SCHEMBL9437241 0.88 MAPT (0.56) MAPTGAAHTTMAPK1CYP2C19
SCHEMBL9437204 0.88 MAPT (0.56) MAPTGAAHTTMAPK1CYP2C19
SCHEMBL12313273 0.87 MAPT (0.53) MAPTGAAHTTMAPK1CYP2C19
SCHEMBL1702573 0.86 MAPT (0.73) MAPTGAAHTTMAPK1POLB
SCHEMBL1702571 0.86 MAPT (0.73) MAPTGAAHTTMAPK1POLB
SCHEMBL14277977 0.85 MAPT (0.42) MAPTGAAHTTMAPK1CYP2C19
SCHEMBL22422719 0.83 MAPT (0.43) MAPTGAAHTTMAPK1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7884245-B2 reacting a diphenylamine with acetic acid and sodium nitrite to obatain a N-nitrosoamine compound, adding thiourea dioxide and NaOH to such reaction solution to reduce nitrosoamine compound to a hydrazine compound, condensing hydrazins with p-diphenylaminobenzaldehyde to form end product hydrazones HODOGAYA CHEMICAL CO., LTD. (JP) 2011-02-08 US claimed
US-20060255322-A1 Methods and compositions for improved electrophoretic display performance WU ZARNG-ARH G 2006-11-16 US claimed
EP-1529242-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER Sipix Imaging, Inc. (US) 2005-05-11 EP claimed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US claimed
WO-2004010206-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER SIPIX IMAGING, INC. (US) 2004-01-29 WO claimed
EP-0462406-B1 An electrophotographic photosensitive material NEC CORP (JP) 1994-04-20 EP claimed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20220197162-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2022-06-23 US disclosed
US-11181838-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2021-11-23 US disclosed
US-10884348-B2 Electrophotographic photoreceptor, and electrophotographic cartridge and image forming apparatus including same MITSUBISHI CHEMICAL CORPORATION (JP) 2021-01-05 US disclosed
US-10795272-B2 Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2020-10-06 US disclosed
EP-3415495-B1 TRIPHENYLAMINE DERIVATIVE, CHARGE TRANSPORT MATERIAL PRODUCED USING SAME, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR TAKASAGO PERFUMERY CO LTD (JP) 2020-09-16 EP disclosed
US-5876892-A POLYCARBONATESILOXANE COPOLYMER SHINDENGEN ELECTRIC MANUFACTURING CO., LTD (JP) 1999-03-02 US disclosed
EP-0462406-B1 An electrophotographic photosensitive material NEC CORP (JP) 1994-04-20 EP disclosed
US-5187036-A Semiconductor lasers NEC CORPORATION (JP) 1993-02-16 US disclosed
EP-0462406-A1 An electrophotographic photosensitive material NEC CORPORATION (JP) 1991-12-27 EP disclosed
US-5061584-A Photosensitive layer contains butadiene, hydrazone and mono-phenol compounds; does not crack when oil drops or fingprints adhere to it SHINDENGEN ELECTRIC MANUFACTURING CO., LTD (JP) 1991-10-29 US disclosed
US-4839252-A PHOTOSENSITIVE LAYER OF A BUTADIENE COMPOUND AND HYDRAZONE COMPOUND; SUPRESSING PHOTO DEGRADATION SHINDENGEN ELECTRIC MANUFACTURING CO., LTD (JP) 1989-06-13 US disclosed
EP-0262761-A1 Organic photoconductor IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10795272-B2 Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same SLC6A19, SLC9A3, SLC9A5 MAPT 3684/4885GAA 4392/4885HTT 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.