Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958044 | 0.88 | PTPN1 (0.77) | PTPN1ALDH1A1GAAMAPTPTPN2 | |
| SCHEMBL15898959 | 0.85 | PTPN1 (0.78) | PTPN1ALDH1A1TDP1PTPN2ERN1 | |
| SCHEMBL13080558 | 0.78 | KDM4E (0.50) | PTPN1ALDH1A1GAAMAPTTDP1 | |
| SCHEMBL5363245 | 0.77 | PTPN1 (1.00) | PTPN1ALDH1A1PTPN2MAOAMAOB | |
| SCHEMBL28016158 | 0.74 | AHR (0.45) | PTPN1ALDH1A1GAAMAPTMAOB | |
| SCHEMBL27697038 | 0.74 | PTPN1 (0.43) | PTPN1MAPTPTPN2ERN1MAOA | |
| SCHEMBL4803818 | 0.74 | MAOA (0.59) | ALDH1A1MAPTMAOAMAOB | |
| SCHEMBL96940 | 0.72 | PTPN1 (0.75) | PTPN1ALDH1A1MAPTTDP1PTPN2 | |
| SCHEMBL30842883 | 0.72 | PTPN1 (0.75) | PTPN1ALDH1A1MAPTTDP1PTPN2 | |
| SCHEMBL7025708 | 0.72 | PTPN1 (0.86) | PTPN1ALDH1A1PTPN2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593435-A1 | SYNTHESIS AND ANTICANCER ACTIVITY OF ARYL AND HETEROARYL-QUINOLIN DERIVATIVES | Tairx, Inc. (TW) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012009519-A1 | SYNTHESIS AND ANTICANCER ACTIVITY OF ARYL AND HETEROARYL-QUINOLIN DERIVATIVES | EFFICIENT PHARMA MANAGEMENT CORP. (TW) | 2012-01-19 | — | — | WO | disclosed |