Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578307 | 0.89 | ALOX5AP (0.87) | ALOX5APALOX5 | |
| SCHEMBL3577926 | 0.84 | ALOX5AP (0.75) | ALOX5APALOX5 | |
| SCHEMBL13349087 | 0.83 | ALOX5AP (0.70) | ALOX5APALOX5 | |
| SCHEMBL3572346 | 0.83 | ALOX5AP (0.72) | ALOX5APALOX5 | |
| SCHEMBL3593845 | 0.82 | ALOX5AP (0.71) | ALOX5APALOX5 | |
| SCHEMBL13314599 | 0.80 | ALOX5AP (0.72) | ALOX5AP | |
| SCHEMBL3582486 | 0.78 | ALOX5AP (1.00) | ALOX5APALOX5 | |
| SCHEMBL3590294 | 0.72 | ALOX5AP (0.93) | ALOX5APALOX5 | |
| SCHEMBL3578341 | 0.70 | ALOX5AP (1.00) | ALOX5APALOX5 | |
| SCHEMBL4319036 | 0.68 | ALOX5AP (0.65) | ALOX5APALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152185-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | CHU LIN | 2010-06-17 | — | — | US | disclosed |
| US-20100152185-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | CHU LIN | 2010-06-17 | — | — | US | disclosed |
| US-7629467-B2 | 5-lipoxygenase activating protein inhibitors; antiatherosclerotic, antiasthmatic, antiallergic, antiinflammatory and cytoprotective agents | MERCK & CO., INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629467-B2 | 5-lipoxygenase activating protein inhibitors; antiatherosclerotic, antiasthmatic, antiallergic, antiinflammatory and cytoprotective agents | MERCK & CO., INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629467-B2 | 5-lipoxygenase activating protein inhibitors; antiatherosclerotic, antiasthmatic, antiallergic, antiinflammatory and cytoprotective agents | MERCK & CO., INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-20060211677-A1 | Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use | MERCK SHARP & DOHME CORP. | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211677-A1 | Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use | ALOX5, ALOX15B, ALOX15 | ALOX5AP 10/4885ALOX5 1/4885 |
| US-20100152185-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | ALOX5, LTC4S, ALOX15 | ALOX5AP 16/4885ALOX5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.