SCHEMBL358778

SCHEMBL358778

NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.78
MAPT P10636 2/20 0.78
MEN1 O00255 1/20 0.78
LMNA P02545 1/20 0.78
MPO P05164 1/20 0.78
TSHR P16473 1/20 0.78
BLM P54132 1/20 0.78
PMP22 Q01453 1/20 0.78
KMT2A Q03164 1/20 0.78
HIF1A Q16665 1/20 0.78
HTR2A P28223 2/20 0.62
ADRB1 P08588 1/20 0.62
HTR1A P08908 1/20 0.62
ADRA2A P08913 1/20 0.62
SLC6A2 P23975 1/20 0.62
HTR1D P28221 1/20 0.62
HTR1B P28222 1/20 0.62
HTR2C P28335 1/20 0.62
HTR1E P28566 1/20 0.62
SLC6A4 P31645 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2726806 1.00 KDM4E (0.78) KDM4EMAPTMEN1LMNAMPO
SCHEMBL29865910 1.00 KDM4E (0.78) KDM4EMAPTMEN1LMNAMPO
SCHEMBL8403649 1.00 KDM4E (0.78) KDM4EMAPTMEN1LMNAMPO
SCHEMBL8403647 1.00 KDM4E (0.78) KDM4EMAPTMEN1LMNAMPO
SCHEMBL29382126 1.00 KDM4E (0.78) KDM4EMAPTMEN1LMNAMPO
SCHEMBL29400974 1.00 KDM4E (0.78) KDM4EMAPTMEN1LMNAMPO
SCHEMBL617181 1.00 KDM4E (0.78) KDM4EMAPTMEN1LMNAMPO
Hydrochloric Acid SCHEMBL3784313 0.98 KDM4E (0.76) KDM4EMAPTMEN1LMNAMPO
Hydrochloric Acid SCHEMBL901447 0.98 KDM4E (0.76) KDM4EMAPTMEN1LMNAMPO
Acetic Acid SCHEMBL25253474 0.94 KDM4E (0.74) KDM4EMAPTMEN1LMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 721 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
WO-2025019764-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS MATTERWORKS INC (US) 2025-01-23 WO claimed
CN-118899403-A Modification structure for lithium metal negative electrode, preparation method and application of lithium metal negative electrode 安徽盟维新能源科技有限公司 2024-11-05 CN claimed
US-20230219973-A1 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF MOLECURE S.A. (PL) 2023-07-13 US claimed
WO-2023119233-A1 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF MOLECURE S.A. (PL) 2023-06-29 WO claimed
US-20220047711-A1 PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS GENENTECH, INC. (US) 2022-02-17 US claimed
EP-3894427-A1 PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS Genentech, Inc. (US) 2021-10-20 EP claimed
CN-113227119-A Photocrosslinked peptides for site-specific conjugation to Fc-containing proteins 基因泰克公司 2021-08-06 CN claimed
WO-2020123275-A1 PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS GENENTECH, INC. (US) 2020-06-18 WO claimed
EP-3401683-A1 DIAGNOSING METABOLIC DISEASE BY THE USE OF A BIOMARKER Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) 2018-11-14 EP claimed
WO-1990014429-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1990-11-29 WO claimed
US-4918196-A HEATING IN PRESENCE OF STRONG BASE, SOLVENT OR SOLVENT-FREE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-04-17 US claimed
US-4725577-A Biologically active lysine containing octapeptides ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 1988-02-16 US claimed
US-4650787-A SOMATOSTATIN ANALOG ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND OF NEW ORLEANS, LOUISIANA, THE, 1987-03-17 US claimed
EP-0203031-A2 Biologically active lysine containing octapeptides The Administrators of The Tulane University Educational Fund (US) 1986-11-26 EP claimed
EP-0193113-A1 Process for optically isomerizing optically active alpha-amino acid amides and process for producing optically active alpha-amino acids MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1986-09-03 EP claimed
US-4497957-A HYDROLYSIS OF DL-TRYPTOPHANE AMIDES BY AMIDASE PRODUCING MICROORGANISMS UBE INDUSTRIES, LTD. (JP) 1985-02-05 US claimed
US-4481362-A ASYMMETRIC HYDROLYSIS OF AMIDE UBE INDUSTRIES, INC. (JP) 1984-11-06 US claimed
EP-0043211-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE TRYPTOPHANES UBE INDUSTRIES, LTD. (JP) 1984-05-09 EP claimed
EP-0043211-A2 Process for preparing optically active tryptophanes UBE INDUSTRIES, LTD. (JP) 1982-01-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219973-A1 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF USP7, USP28, USP1 KDM4E 518/4885MAPT 1555/4885MEN1 2177/4885
US-20220047711-A1 PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS FCGR2A, FCGR3B, DNPEP KDM4E 4325/4885MAPT 3486/4885MEN1 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.