Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13200405 | 0.87 | SCN9A (0.49) | SCN9ASCN10ARAB9APLA2G10PLA2G5 | |
| SCHEMBL13200416 | 0.86 | SCN9A (0.46) | SCN9ASCN10ARAB9APLA2G10PLA2G5 | |
| SCHEMBL6283002 | 0.81 | CYP2D6 (0.65) | SCN9ASCN10AKMT2APLA2G10PLA2G5 | |
| SCHEMBL6282329 | 0.81 | PLA2G10 (0.47) | SCN9ASCN10AKMT2APLA2G10PLA2G5 | |
| SCHEMBL3582057 | 0.79 | KMT2A (0.61) | SCN9AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL766459 | 0.78 | RBP4 (0.57) | SCN9ASCN10AKMT2AMEN1KDM4E | |
| SCHEMBL6283587 | 0.78 | LMNA (0.48) | SCN9ASCN10AKMT2AMEN1PLA2G10 | |
| SCHEMBL14019898 | 0.76 | NPC1 (0.51) | SCN9AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13217676 | 0.76 | SCN9A (0.43) | SCN9ASCN10APLA2G10PLA2G5DRD2 | |
| SCHEMBL13200403 | 0.76 | SCN9A (0.43) | SCN9ASCN10APLA2G10PLA2G5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127459-A1 | GPR139 RECEPTOR MODULATORS | BLACKTHORN THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021127459-A1 | GPR139 RECEPTOR MODULATORS | BLACKTHORN THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | SCN9A 1304/4885SCN10A 1290/4885KMT2A 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.