Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SDCBP | O00560 | 6/20 | 0.38 |
| ▸ | SDC2 | P34741 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009031 | 0.79 | ITGB3 (0.56) | NPC1RAB9ATHRBSDCBPSDC2 | |
| SCHEMBL2011706 | 0.70 | ALOX15 (0.47) | KMT2AMEN1MAPTALDH1A1ITGB3 | |
| SCHEMBL2009033 | 0.69 | ITGB3 (0.46) | KMT2AMEN1MAPTITGB3ITGA2B | |
| SCHEMBL2005612 | 0.67 | ITGB3 (0.56) | NPC1RAB9ATHRBSDCBPSDC2 | |
| SCHEMBL2008739 | 0.66 | ITGB3 (0.41) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL2009666 | 0.65 | ITGB3 (0.38) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL2008615 | 0.65 | ITGB3 (0.43) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL2012100 | 0.65 | HPGD (0.45) | NPC1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2007548 | 0.64 | ITGB3 (0.37) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL2011006 | 0.64 | GAA (0.37) | KMT2AMEN1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759387-B2 | Fibrinogen receptor antagonists and their use | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | FGB, F13B, F2 | NPC1 4226/4885RAB9A 2816/4885THRB 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.