Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597920 | 0.92 | ALDH1A1 (0.55) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL14390903 | 0.88 | SMN1; SMN2 (0.47) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL3580685 | 0.84 | PDE5A (0.48) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL3591628 | 0.82 | ADORA2A (0.56) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL3594942 | 0.81 | PDE5A (0.46) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL22215646 | 0.81 | ALDH1A1 (0.82) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL3592649 | 0.80 | PDE5A (0.46) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL3590688 | 0.79 | ADORA2A (0.56) | ALDH1A1HPGDNPSR1KDM4EMAPT | |
| SCHEMBL3592516 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDNPSR1KDM4ETDP1 | |
| SCHEMBL3595419 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDNPSR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009973-A1 | Integrase Inhibitors 3 | AVEXA LIMITED (AU) | 2010-01-14 | — | — | US | disclosed |
| US-20100009973-A1 | Integrase Inhibitors 3 | AVEXA LIMITED (AU) | 2010-01-14 | — | — | US | disclosed |
| US-20100009973-A1 | Integrase Inhibitors 3 | AVEXA LIMITED (AU) | 2010-01-14 | — | — | US | disclosed |
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009973-A1 | Integrase Inhibitors 3 | TYMP, IMPDH1, IMPDH2 | ALDH1A1 1001/4885HPGD 1588/4885NPSR1 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.