SCHEMBL3590916

SCHEMBL3590916

NC(=O)OOc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
PKM P14618 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CTNNB1 P35222 1/20 0.44
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4592607 0.80 ALOX15 (0.44) PARP10CYP2D6PKMTSHRTDP1
SCHEMBL8731765 0.80 ALOX15 (0.44) PARP10CYP2D6PKMTSHRTDP1
SCHEMBL10388997 0.79 ALOX15 (0.45) PARP10SMN1; SMN2CYP1A2CYP2D6PKM
SCHEMBL4466865 0.78 ALOX15 (0.43) PARP10CYP2D6PKMTSHRTDP1
SCHEMBL4010662 0.76 ALDH1A1 (0.43) PARP10CYP2D6PKMTSHRTDP1
SCHEMBL247575 0.76 ELANE (0.45) TSHRTDP1L3MBTL1CYP3A4MAPT
Benzene SCHEMBL9407301 0.76 ELANE (0.45) TSHRTDP1L3MBTL1CYP3A4MAPT
Carbamic Acid Phenyl Ester SCHEMBL7566 0.75 MEN1 (0.70) PARP10MEN1KMT2ACTNNB1TSHR
SCHEMBL5244678 0.74 F2 (0.70) PARP10MEN1KMT2APKMTSHR
Ammonia Solution, Strong SCHEMBL11121327 0.74 ELANE (0.44) TSHRTDP1L3MBTL1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697376-B1 SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-06-18 EP claimed
EP-0183174-B1 SUBSTITUTED PHENOXY UREA, PROCESSES FOR ITS PREPARATION AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-26 EP claimed
EP-0183174-A2 Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1986-06-04 EP claimed
JP-52033640-A None JP disclosed
CN-109971471-B Fluorescent carbon dot for detecting phenoxy group-containing carbamate pesticide and application thereof 中科(大连)快检科技有限公司 2022-01-14 CN disclosed
EP-2057140-B1 MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS ASTRAZENECA AB (SE) 2012-08-08 EP disclosed
US-7750003-B2 Compounds-943 ASTRAZENECA AB (SE) 2010-07-06 US disclosed
US-7618717-B2 Light emitting device FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
EP-2057140-A1 MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS AstraZeneca AB (SE) 2009-05-13 EP disclosed
US-20080171743-A1 Transcutaneous immunostimulation ASTRAZENECA AB (SE) 2008-07-17 US disclosed
WO-2008023159-A1 MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS ASTRAZENECA AB (SE) 2008-02-28 WO disclosed
WO-2001042243-A2 PROTEIN KINASE INHIBITORS ADVANCED MEDICINE, INC. (US) 2001-06-14 WO disclosed
US-5112385-A Useful in rice paddies KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-05-12 US disclosed
EP-0469450-A1 p-Acylaminophenoxycarbamates and Derivatives HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1992-02-05 EP disclosed
US-4968341-A PRE-AND POSTEMERGENCE HERBICIDES KUMIAI CHEMICAL INDUSTRY CO. (JP) 1990-11-06 US disclosed
EP-0183174-B1 SUBSTITUTED PHENOXY UREA, PROCESSES FOR ITS PREPARATION AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-26 EP disclosed
EP-0183174-A2 Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1986-06-04 EP disclosed
US-4410697-A CARBAMATE, AMINE, TERTIARY AMINE CATALYST REANAL FINOMVEGYSZERGYAR (HU) 1983-10-18 US disclosed
WO-1981002156-A1 PROCESS FOR THE PREPARATION OF N-ARYL-N'-(MONO-OR DISUBSTIUTED)-UREA DERIVATIVES REANAL FINOMVEGYSZERGYAR (HU) 1981-08-06 WO disclosed
JP-S5233640-A PROCESS FOR PREPARATION OF BENZENEDICARBOXYLIC ACID AMIDES BANYU PHARMACEUT CO LTD 1977-03-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171743-A1 Transcutaneous immunostimulation NFATC1, TLR9, MTOR PARP10 3824/4885MEN1 2336/4885KMT2A 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.