SCHEMBL4466865

SCHEMBL4466865

[NH]C(=O)OOc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.43
F2 P00734 1/20 0.42
LMNA P02545 1/20 0.42
SRC P12931 1/20 0.39
LTA4H P09960 1/20 0.39
TSHR P16473 1/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
PARP10 Q53GL7 1/20 0.39
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SRD5A2 P31213 1/20 0.38
PKM P14618 1/20 0.38
AKR1C3 P42330 1/20 0.38
CYP2D6 P10635 1/20 0.37
CA5A P35218 1/20 0.37
CA5B Q9Y2D0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731765 0.82 ALOX15 (0.44) ALOX15F2LMNASRCLTA4H
SCHEMBL4592607 0.82 ALOX15 (0.44) ALOX15F2LMNASRCLTA4H
SCHEMBL3590916 0.78 PARP10 (0.47) ALOX15F2LMNASRCLTA4H
SCHEMBL4010662 0.78 ALDH1A1 (0.43) ALOX15F2LMNASRCLTA4H
Benzene SCHEMBL9407301 0.78 ELANE (0.45) ALOX15F2LMNATSHRATM
SCHEMBL247575 0.78 ELANE (0.45) ALOX15F2LMNATSHRATM
SCHEMBL10388997 0.76 ALOX15 (0.45) ALOX15F2LMNALTA4HPARP10
SCHEMBL5244678 0.76 F2 (0.70) ALOX15F2LMNATSHRL3MBTL1
Ammonia Solution, Strong SCHEMBL11121327 0.76 ELANE (0.44) ALOX15F2LMNATSHRATM
SCHEMBL11508266 0.76 ELANE (0.44) ALOX15F2LMNATSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697376-B1 SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-06-18 EP claimed
US-7618717-B2 Light emitting device FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
US-20050191519-A1 Light emitting device FUJI PHOTO FILM CO., LTD. 2005-09-01 US disclosed