Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592607 | 0.80 | ALOX15 (0.44) | ALDH1A1ALOX15F2LMNASRC | |
| SCHEMBL8731765 | 0.80 | ALOX15 (0.44) | ALOX15F2LMNASRCL3MBTL1 | |
| SCHEMBL4466865 | 0.78 | ALOX15 (0.43) | ALOX15F2LMNASRCL3MBTL1 | |
| SCHEMBL11300560 | 0.77 | LDHA (0.44) | LMNAL3MBTL1 | |
| SCHEMBL9601104 | 0.76 | LTA4H (0.38) | ALDH1A1ALOX15F2LMNASRC | |
| SCHEMBL3590916 | 0.76 | PARP10 (0.47) | ALOX15F2LMNASRCL3MBTL1 | |
| Benzene SCHEMBL9407301 | 0.76 | ELANE (0.45) | ALDH1A1ALOX15F2LMNAL3MBTL1 | |
| SCHEMBL247575 | 0.76 | ELANE (0.45) | ALDH1A1ALOX15F2LMNAL3MBTL1 | |
| Benzene SCHEMBL7925278 | 0.75 | TDP1 (0.50) | ALDH1A1ALOX15L3MBTL1TDP1ATM | |
| SCHEMBL3302 | 0.75 | TDP1 (0.50) | ALDH1A1ALOX15L3MBTL1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126361-A1 | Optically active propionic-acid derivatives | BAYER AG (DE) | 1984-11-28 | — | — | EP | claimed |
| EP-0014900-B1 | CARBONYLALKYL ESTERS OF PHENOXYCARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AS WELL AS DEFOLIANTS AND DESICCANTS | BAYER AG (DE) | 1982-06-02 | — | — | EP | claimed |
| EP-0014900-A1 | Carbonylalkyl esters of phenoxycarboxylic acids, process for their preparation and their use as herbicides as well as defoliants and desiccants | BAYER AG (DE) | 1980-09-03 | — | — | EP | claimed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | claimed |
| EP-2074107-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008057254-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0573467-B1 | NEUROLEPTIC PERHYDRO-1H-PYRIDO 1,2-a]PYRAZINES | PFIZER (US) | 1995-05-31 | — | — | EP | disclosed |
| EP-0613479-A1 | MARCFORTINE/PARAHERQUAMIDE DERIVATIVES USEFUL AS ANTIPARASITIC AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0573467-A1 | NEUROLEPTIC PERHYDRO-1H-PYRIDO 1,2-a]PYRAZINES. | PFIZER (US) | 1993-12-15 | — | — | EP | disclosed |
| WO-1993010120-A1 | MARCFORTINE/PARAHERQUAMIDE DERIVATIVES USEFUL AS ANTIPARASITIC AGENTS | THE UPJOHN COMPANY (US) | 1993-05-27 | — | — | WO | disclosed |
| US-5194661-A | Carbamyl ether derivatives | ICI AMERICAS INC. (US) | 1993-03-16 | — | — | US | disclosed |
| US-5099059-A | Phenoxyalkylcarbamates | ZENECA LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |
| US-5078783-A | Especially preemergence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0126361-A1 | Optically active propionic-acid derivatives | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0014880-B1 | PHENOXYCARBOXYLIC ACID AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0014900-B1 | CARBONYLALKYL ESTERS OF PHENOXYCARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AS WELL AS DEFOLIANTS AND DESICCANTS | BAYER AG (DE) | 1982-06-02 | — | — | EP | disclosed |
| EP-0014900-A1 | Carbonylalkyl esters of phenoxycarboxylic acids, process for their preparation and their use as herbicides as well as defoliants and desiccants | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |