SCHEMBL3590924

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL841924	0.83	MAPT (0.62)	GABRA5ALDH1A1MAPTKMT2ANNMT
	SCHEMBL14480387	0.83	ACACB (0.48)	ALDH1A1MAPTKMT2ANNMTACACB
	SCHEMBL5013585	0.81	NNMT (0.67)	ALDH1A1MAPTNNMTACACBSMN1; SMN2
	SCHEMBL30464201	0.81	NNMT (0.67)	ALDH1A1MAPTNNMTACACBSMN1; SMN2
	SCHEMBL27875916	0.81	ALDH1A1 (0.46)	ALDH1A1MAPTKMT2ANNMTACACB
	SCHEMBL9944378	0.79	HDAC1 (0.56)	CA12CA1CA2CA7CA9
	SCHEMBL28934086	0.78	CA12 (0.53)	CA12CA1CA2CA7CA9
	SCHEMBL4655916	0.78	SMN1; SMN2 (0.55)	CA12CA1CA2CA7CA9
	SCHEMBL3869968	0.78	POLB (0.58)	CA12CA1CA2CA7CA9
	SCHEMBL9944384	0.78	CA12 (0.53)	CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.