Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358757 | 0.96 | MAPT (0.65) | MAPTGAAALDH1A1TP53POLB | |
| SCHEMBL35916 | 0.96 | MAPT (0.65) | MAPTGAAALDH1A1TP53POLB | |
| Ammonia Solution, Strong SCHEMBL27977263 | 0.94 | MAPT (0.62) | MAPTGAAALDH1A1TP53POLB | |
| Hydrochloric Acid SCHEMBL29378616 | 0.94 | GAA (0.68) | MAPTGAAALDH1A1TP53POLB | |
| Hydrochloric Acid SCHEMBL33976 | 0.94 | GAA (0.68) | MAPTGAAALDH1A1TP53POLB | |
| Hydrochloric Acid SCHEMBL29356501 | 0.94 | GAA (0.68) | MAPTGAAALDH1A1TP53POLB | |
| Hydrochloric Acid SCHEMBL1453993 | 0.94 | GAA (0.68) | MAPTGAAALDH1A1TP53POLB | |
| SCHEMBL8091658 | 0.93 | MAPT (0.61) | MAPTGAAALDH1A1TP53POLB | |
| Hydrochloric Acid SCHEMBL29148900 | 0.93 | GAA (0.66) | MAPTGAAALDH1A1TP53POLB | |
| 2,4-Diaminophenol SCHEMBL19327374 | 0.88 | ALDH1A1 (0.56) | MAPTGAAALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4454633-A1 | SOLID COLOURING AGENT EMULSION FOR MANUFACTURING HAIR DYE | Roca Pares, Albert (ES) | 2024-10-30 | — | — | EP | disclosed |
| CN-117017809-B | Dioxygen-free hair dye paste and preparation method thereof | 珠海横琴一果投资合伙企业(有限合伙) | 2024-07-19 | — | — | CN | disclosed |
| CN-117017809-A | Dioxygen-free hair dye paste and preparation method thereof | 珠海横琴一果投资合伙企业(有限合伙) | 2023-11-10 | — | — | CN | disclosed |
| US-20200345603-A1 | PRODUCT FOR THE OXIDATIVE DYEING OF HAIR CONTAINING SPECIAL DEVELOPERS, COUPLERS AND ALKALIZING AGENTS | HENKEL AG & CO. KGAA (DE) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200345603-A1 | PRODUCT FOR THE OXIDATIVE DYEING OF HAIR CONTAINING SPECIAL DEVELOPERS, COUPLERS AND ALKALIZING AGENTS | QDPR, PNMT, DDT | MAPT 1891/4885GAA 4675/4885ALDH1A1 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.