Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29378616 | 1.00 | GAA (0.68) | GAAMAPTALDH1A1KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL29356501 | 1.00 | GAA (0.68) | GAAMAPTALDH1A1KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL1453993 | 1.00 | GAA (0.68) | GAAMAPTALDH1A1KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL29148900 | 0.98 | GAA (0.66) | GAAMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL35916 | 0.98 | MAPT (0.65) | GAAMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL29358757 | 0.98 | MAPT (0.65) | GAAMAPTALDH1A1KDM4ETP53 | |
| Ammonia Solution, Strong SCHEMBL27977263 | 0.96 | MAPT (0.62) | GAAMAPTALDH1A1KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL22612486 | 0.94 | MAPT (0.61) | GAAMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL8091658 | 0.94 | MAPT (0.61) | GAAMAPTALDH1A1KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL6576256 | 0.91 | GAA (0.66) | GAAMAPTALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12396938-B2 | Compositions and methods for coloring hair | L'OREAL (FR) | 2025-08-26 | — | — | US | claimed |
| US-12268769-B2 | Hair coloring compositions | L'OREAL (FR) | 2025-04-08 | — | — | US | claimed |
| US-12257330-B2 | Hair coloring compositions and methods of use | L'OREAL (FR) | 2025-03-25 | — | — | US | claimed |
| US-12109289-B2 | Compositions for imparting color and tone to the hair | L'OREAL (FR) | 2024-10-08 | — | — | US | claimed |
| CN-117017809-B | Dioxygen-free hair dye paste and preparation method thereof | 珠海横琴一果投资合伙企业(有限合伙) | 2024-07-19 | — | — | CN | claimed |
| EP-3697370-B1 | HAIR COLORING COMPOSITION COMPRISING MICROCAPSULES | FIRMENICH & CIE (CH) | 2024-06-12 | — | — | EP | claimed |
| CN-117530891-B | Hair dye with low irritation and preparation method thereof | 佛山市喜妆化妆品有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-20240148629-A1 | HAIR COLORING COMPOSITIONS | L'OREAL (FR) | 2024-05-09 | — | — | US | claimed |
| CN-111417373-B | Hair dyeing composition comprising microcapsules | 弗门尼舍有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117618310-A | Hair dye for reducing hair damage and preparation method thereof | 佛山市喜妆化妆品有限公司 | 2024-03-01 | — | — | CN | claimed |
| WO-2015165949-A1 | PROCESS FOR BLEACHING OR DYEING KERATIN FIBRES USING AN OXIDIZING COMPOSITION AND UV-VISIBLE RADIATION | L'OREAL (FR) | 2015-11-05 | — | — | WO | claimed |
| CN-103396327-B | Preparation technology of 2, 4-diamino-phenoxyethanol hydrochloride | YIXING XINYU CHEMICALS CO LTD | 2015-01-07 | — | — | CN | claimed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | claimed |
| EP-1429715-B1 | HAIR COLOURING COMPOSITIONS | BOOTS CO PLC (GB) | 2010-11-24 | — | — | EP | claimed |
| US-7172632-B2 | Hair coloring compositions | THE BOOTS COMPANY, PLC (GB) | 2007-02-06 | — | — | US | claimed |
| US-20050039269-A1 | Hair colouring compositions | BOOTS COMPANY PLC, THE (GB) | 2005-02-24 | — | — | US | claimed |
| US-6702863-B1 | SINGLE PACKAGE AEROSOL CONPRISED OF 5,6-DIHYDROXYINDOLINE, LACCASE, WATER AND PROPELLANT; NONIRRITATING; STORAGE STABLE | LION CORPORATION (JP) | 2004-03-09 | — | — | US | claimed |
| US-6342079-B1 | 1-(2,5-DIPHENYL)ETHANOL FOR HAIR DYES | BRISTOL-MYERS SQUIBB COMPANY | 2002-01-29 | — | — | US | claimed |
| WO-2001054656-A1 | NOVEL PRIMARY INTERMEDIATE FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-02 | — | — | WO | claimed |
| EP-1120105-A2 | 1-(2,5-diaminophenyl)ethanol and its use in oxidative hair dyeing | Bristol-Myers Squibb Company (US) | 2001-08-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148629-A1 | HAIR COLORING COMPOSITIONS | PLIN5, GK, PLIN3 | GAA 3647/4885MAPT 4097/4885ALDH1A1 227/4885 |
| US-12268769-B2 | Hair coloring compositions | PLIN5, GK, PLIN3 | GAA 3647/4885MAPT 4097/4885ALDH1A1 227/4885 |
| US-12257330-B2 | Hair coloring compositions and methods of use | SGMS1, PHOSPHO1, SGMS2 | GAA 4096/4885MAPT 3030/4885ALDH1A1 404/4885 |
| US-12109289-B2 | Compositions for imparting color and tone to the hair | TYR, INMT, AADAT | GAA 4773/4885MAPT 596/4885ALDH1A1 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.