Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27977263

N.Nc1ccc(OCCO)c(N)c1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.62
GAA P10253 3/20 0.62
ALDH1A1 P00352 3/20 0.62
TP53 P04637 2/20 0.62
POLB P06746 2/20 0.62
USP2 O75604 2/20 0.62
KDM4E B2RXH2 2/20 0.62
MEN1 O00255 1/20 0.62
CASP1 P29466 1/20 0.62
HTT P42858 1/20 0.62
CASP7 P55210 1/20 0.62
KMT2A Q03164 1/20 0.62
ATM Q13315 1/20 0.62
PRSS1 P07477 8/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.41
IDO1 P14902 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29148900 0.98 GAA (0.66) MAPTGAAALDH1A1TP53POLB
SCHEMBL35916 0.98 MAPT (0.65) MAPTGAAALDH1A1TP53POLB
SCHEMBL29358757 0.98 MAPT (0.65) MAPTGAAALDH1A1TP53POLB
Hydrochloric Acid SCHEMBL33976 0.96 GAA (0.68) MAPTGAAALDH1A1TP53POLB
Hydrochloric Acid SCHEMBL1453993 0.96 GAA (0.68) MAPTGAAALDH1A1TP53POLB
Hydrochloric Acid SCHEMBL29356501 0.96 GAA (0.68) MAPTGAAALDH1A1TP53POLB
Hydrochloric Acid SCHEMBL29378616 0.96 GAA (0.68) MAPTGAAALDH1A1TP53POLB
Hydrochloric Acid SCHEMBL22612486 0.94 MAPT (0.61) MAPTGAAALDH1A1TP53POLB
SCHEMBL8091658 0.94 MAPT (0.61) MAPTGAAALDH1A1TP53POLB
2,4-Diaminophenol SCHEMBL19327374 0.90 ALDH1A1 (0.56) MAPTGAAALDH1A1TP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103957883-A Pretreatment agents for keratin fibers comprising 4-morpholino-methyl-substituted silicone(s) HENKEL AG & CO KGAA 2014-07-30 CN disclosed