Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463118 | 0.79 | ADRA2C (0.43) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL3585825 | 0.77 | ADRA2C (0.39) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL3584990 | 0.76 | ALDH1A1 (0.47) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL3589113 | 0.76 | DRD2 (0.50) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL4173801 | 0.76 | DRD2 (0.45) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL3583431 | 0.75 | ASIC3 (0.40) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL14355831 | 0.75 | ADRA2C (0.56) | ADRA2CDRD2DRD3MAPTMAPK1 | |
| SCHEMBL3595550 | 0.75 | DRD2 (0.55) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL3584991 | 0.75 | ALDH1A1 (0.41) | ADRA2CDRD2DRD3MAPTKDM4E | |
| SCHEMBL188362 | 0.74 | ADRA2C (0.42) | ADRA2CDRD2DRD3MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | ADRA2C 3317/4885DRD2 4782/4885DRD3 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.