Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593691 | 1.00 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DRARB | |
| SCHEMBL6138195 | 0.91 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DRARB | |
| SCHEMBL6138471 | 0.86 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DRARB | |
| SCHEMBL6138536 | 0.84 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DRARB | |
| SCHEMBL3593693 | 0.84 | MEN1 (0.42) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3596775 | 0.84 | MEN1 (0.42) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3596771 | 0.84 | MEN1 (0.42) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3485010 | 0.80 | PLA2G4B (0.47) | PDE4APDE4BPDE4CPDE4DCYSLTR2 | |
| SCHEMBL3485012 | 0.80 | PLA2G4B (0.47) | PDE4APDE4BPDE4CPDE4DCYSLTR2 | |
| SCHEMBL3484740 | 0.80 | PLA2G4B (0.47) | PDE4APDE4BPDE4CPDE4DCYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674825-B2 | Dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | PC, GOT2, SDHA | PDE4A 1833/4885PDE4B 1835/4885PDE4C 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.