⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600491 | 0.84 | — | — | |
| SCHEMBL3593792 | 0.78 | ADRB2 (0.31) | — | |
| SCHEMBL3593791 | 0.65 | DUT (0.37) | — | |
| SCHEMBL12956926 | 0.63 | CRBN (0.36) | — | |
| SCHEMBL7746322 | 0.61 | ELANE (0.41) | — | |
| SCHEMBL11625437 | 0.61 | DRD2 (0.46) | — | |
| SCHEMBL17542986 | 0.61 | SRD5A1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL11623086 | 0.60 | DRD2 (0.45) | — | |
| SCHEMBL7097075 | 0.59 | KDM4E (0.50) | — | |
| SCHEMBL12956923 | 0.58 | CRBN (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |