Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.47 |
| ▸ | MERTK | Q12866 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13504912 | 0.91 | MELK (0.49) | ALDH1A1CYP2C19MEN1CYP1A2CYP2D6 | |
| SCHEMBL3608825 | 0.90 | SCD5 (0.53) | SCD5ALDH1A1CYP2C19MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3616292 | 0.90 | SLC2A1 (0.50) | ALDH1A1CYP2C19MEN1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL3612162 | 0.87 | SLC2A1 (0.52) | SCD5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3610936 | 0.84 | MELK (0.60) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13504906 | 0.83 | SLC2A1 (0.59) | ALDH1A1CYP2C19MEN1CYP1A2MAPT | |
| SCHEMBL13504916 | 0.82 | LMNA (0.56) | ALDH1A1CYP2C19MEN1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL3603607 | 0.82 | SLC2A1 (0.61) | ALDH1A1CYP2C19MEN1CYP1A2MAPT | |
| Hydrochloric Acid SCHEMBL3611947 | 0.82 | LMNA (0.56) | ALDH1A1CYP2C19MEN1CYP1A2CYP2D6 | |
| SCHEMBL3605849 | 0.80 | NAMPT (0.49) | SCD5CYP2C19MEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | claimed |
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | SCD5 4/4885AXL 4365/4885TYRO3 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.