Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 7/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | SCD | O00767 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605849 | 0.91 | NAMPT (0.49) | SCD5NAMPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL3593878 | 0.90 | SCD5 (0.47) | SCD5ALDH1A1MEN1CYP1A2CYP2D6 | |
| SCHEMBL3611274 | 0.90 | NAMPT (0.56) | SCD5NAMPTSCD | |
| SCHEMBL13504884 | 0.88 | NAMPT (0.60) | SCD5NAMPTSCDALDH1A1RPS6KA2 | |
| SCHEMBL3611305 | 0.87 | NAMPT (0.63) | SCD5NAMPTSCDALDH1A1MEN1 | |
| SCHEMBL3608690 | 0.87 | TAS2R8 (0.52) | SCD5NAMPTSCDALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3612494 | 0.87 | NAMPT (0.59) | SCD5NAMPTSCDALDH1A1RPS6KA2 | |
| SCHEMBL3602956 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL13504905 | 0.85 | ITK (0.59) | NAMPTSCDALDH1A1CYP2C19ROCK2 | |
| Hydrochloric Acid SCHEMBL3601453 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MEN1CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | claimed |
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | SCD5 4/4885NAMPT 869/4885SCD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.