Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5890969 | 0.82 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL5891165 | 0.82 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL82589 | 0.80 | MAPT (0.65) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| Potassium Ion SCHEMBL1577462 | 0.78 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL6710649 | 0.78 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL16014474 | 0.78 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9579935 | 0.78 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL519624 | 0.78 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL21244024 | 0.78 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL18867934 | 0.78 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754743-B2 | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20090018056-A1 | Heteroarylcarbamoylbenzene derivatives | MSD K.K. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-7432287-B2 | Heteroarylcarbamoylbenzene derivative | BANYU PHARMECEUTICAL CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | MSD K.K. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1600442-A1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-0436938-B1 | Silver halide color photographic material containing yellow colored cyan coupler | FUJI PHOTO FILM CO LTD (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5498513-A | BENZOTRIAZOLE DIR COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0451526-B1 | Silver halide colour photographic materials | FUJI PHOTO FILM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| EP-0451526-A2 | Silver halide colour photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-4927743-A | Silver halide photographic light-sensitive materials having specified coupler, dir coupler and silver coverage | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018056-A1 | Heteroarylcarbamoylbenzene derivatives | GCK, GCKR, KHK | LMNA 4416/4885ALDH1A1 707/4885SMN1; SMN2 4432/4885 |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | GCK, GCKR, GALK1 | LMNA 3952/4885ALDH1A1 902/4885SMN1; SMN2 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.