Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908188 | 0.80 | ESR2 (0.55) | LMNAALDH1A1ENPP2ESR1CA12 | |
| SCHEMBL5623176 | 0.80 | ALDH1A1 (0.71) | LMNAALDH1A1ENPP2ESR1CA12 | |
| SCHEMBL5890969 | 0.80 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2HTTCA12 | |
| SCHEMBL5891165 | 0.80 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2HTTCA12 | |
| SCHEMBL82589 | 0.78 | MAPT (0.65) | LMNAALDH1A1SMN1; SMN2HTTCA12 | |
| SCHEMBL3594764 | 0.78 | LMNA (0.61) | LMNAALDH1A1SMN1; SMN2HTTCA12 | |
| SCHEMBL25196296 | 0.78 | LMNA (0.74) | LMNAALDH1A1ESR1ESR2MAPT | |
| SCHEMBL5249012 | 0.77 | SMN1; SMN2 (0.57) | LMNAALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| Potassium Ion SCHEMBL1577462 | 0.76 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTCA12 | |
| SCHEMBL21244024 | 0.76 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2HTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153642-B | Indole and azaindole halogenated allylamine derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2022-05-17 | — | — | CN | disclosed |
| US-10717734-B2 | Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof | PHARMAXIS LTD. (AU) | 2020-07-21 | — | — | US | disclosed |
| US-10717734-B2 | Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof | PHARMAXIS LTD. (AU) | 2020-07-21 | — | — | US | disclosed |
| US-20190119269-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2019-04-25 | — | — | US | disclosed |
| US-20190119269-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2019-04-25 | — | — | US | disclosed |
| US-20190071396-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2019-03-07 | — | — | US | disclosed |
| EP-3438087-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2019-02-06 | — | — | EP | disclosed |
| US-20180086698-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-29 | — | — | US | disclosed |
| US-20180086698-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-29 | — | — | US | disclosed |
| EP-2844637-B1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-4927743-A | Silver halide photographic light-sensitive materials having specified coupler, dir coupler and silver coverage | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| US-4505929-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| EP-0034263-B1 | SUBSTITUTED BENZONITRILES AND COMPOSITIONS FOR INHIBITING VIRUSES | THE DOW CHEMICAL COMPANY (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4332820-A | ESPECIALLY EFFECTIVE AGAINST PICORNOVIRUSES | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0034263-A2 | Substituted benzonitriles and compositions for inhibiting viruses | THE DOW CHEMICAL COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4283418-A | ANTIPLASMIN AND ANTITRYPSIN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4254144-A | Substituted benzonitriles having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4074059-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-3979203-A | Sulfonamido herbicidal compositions and plant control methods using the same | AMERICAN CYANAMID COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071396-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | AOC3, HAO1, VAPA | LMNA 1211/4885ALDH1A1 33/4885SMN1; SMN2 1418/4885 |
| US-20180086698-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | AOC3, HAO1, VAPA | LMNA 1211/4885ALDH1A1 33/4885SMN1; SMN2 1418/4885 |
| US-10717734-B2 | Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof | IDO1, IDO2, INMT | LMNA 1651/4885ALDH1A1 322/4885SMN1; SMN2 4655/4885 |
| US-20190119269-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | IDO1, IDO2, INMT | LMNA 1651/4885ALDH1A1 322/4885SMN1; SMN2 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.