Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891165 | 1.00 | LMNA (0.64) | LMNASMN1; SMN2ALDH1A1HTTPKM | |
| SCHEMBL4073854 | 0.91 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1HTTPKM | |
| SCHEMBL3082587 | 0.89 | CA12 (0.57) | LMNASMN1; SMN2ALDH1A1HTTPKM | |
| Hydrochloric Acid SCHEMBL28477859 | 0.89 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1HTTPKM | |
| SCHEMBL694839 | 0.87 | LMNA (0.52) | LMNASMN1; SMN2ALDH1A1HTTPKM | |
| SCHEMBL3642059 | 0.84 | CA12 (0.59) | SMN1; SMN2ALDH1A1RAB9ACA12CA2 | |
| SCHEMBL82589 | 0.82 | MAPT (0.65) | LMNASMN1; SMN2ALDH1A1HTTCA12 | |
| SCHEMBL3594764 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1HTTPKM | |
| SCHEMBL13575399 | 0.81 | ALDH1A1 (0.49) | LMNASMN1; SMN2ALDH1A1HTTPKM | |
| Potassium Ion SCHEMBL1577462 | 0.80 | LMNA (0.59) | LMNASMN1; SMN2ALDH1A1HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053173-B2 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-05-30 | — | — | US | claimed |
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-05-13 | — | — | US | claimed |
| US-7053173-B2 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1380572-A1 | POLYMERCAPTOPOLYPHENYLS AND METHOD FOR SYNTHESIS THEREOF | Japan Science and Technology Corporation (JP) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | TMT1A, MSMO1, TST | LMNA 2133/4885SMN1; SMN2 2154/4885ALDH1A1 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.