Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596185 | 1.00 | PTGER4 (0.37) | PTGER4PPARGGPR132ALDH1A1LMNA | |
| SCHEMBL6001905 | 0.89 | PPARG (0.43) | PTGER4PPARGALDH1A1LMNA | |
| SCHEMBL7605227 | 0.87 | TRPA1 (0.38) | PTGER4PPARGALDH1A1LTB4R2TRPA1 | |
| SCHEMBL7605223 | 0.87 | TRPA1 (0.38) | PTGER4PPARGALDH1A1LTB4R2TRPA1 | |
| SCHEMBL3606823 | 0.82 | NFE2L2 (0.47) | PTGER4ALDH1A1LMNATDP1 | |
| SCHEMBL3606819 | 0.82 | NFE2L2 (0.47) | PTGER4ALDH1A1LMNATDP1 | |
| SCHEMBL7622355 | 0.76 | PTGFR (0.50) | PTGER4LTB4R2 | |
| SCHEMBL6280253 | 0.75 | MAPT (0.52) | PTGER4LTB4R2TRPA1 | |
| SCHEMBL6280250 | 0.75 | MAPT (0.52) | PTGER4LTB4R2TRPA1 | |
| SCHEMBL3129248 | 0.75 | HTT (0.55) | PTGER4LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674825-B2 | Dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2010-03-09 | — | — | US | disclosed |