Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 10/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600337 | 0.89 | PPARG (0.43) | PTGFR | |
| SCHEMBL3596181 | 0.76 | PTGER4 (0.37) | PTGER4LTB4R2 | |
| SCHEMBL3596185 | 0.76 | PTGER4 (0.37) | PTGER4LTB4R2 | |
| SCHEMBL8697433 | 0.74 | NPSR1 (0.45) | NPSR1 | |
| SCHEMBL2675279 | 0.73 | ELANE (0.38) | NPSR1 | |
| SCHEMBL7438547 | 0.72 | NPSR1 (0.36) | NPSR1 | |
| SCHEMBL19812305 | 0.71 | L3MBTL1 (0.40) | NPSR1DHFR | |
| SCHEMBL8700617 | 0.71 | ADRA2A (0.41) | NPSR1LTB4RLTB4R2 | |
| SCHEMBL19812300 | 0.71 | TAAR1 (0.37) | NPSR1 | |
| SCHEMBL9853837 | 0.70 | L3MBTL1 (0.44) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216222-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019776-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |