Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597010 | 1.00 | LTA4H (0.42) | LTA4HCASP3ESR2FAPFAAH | |
| SCHEMBL3597998 | 0.91 | LTA4H (0.44) | LTA4HESR2FAAH | |
| SCHEMBL3597992 | 0.91 | LTA4H (0.44) | LTA4HESR2FAAH | |
| SCHEMBL9968590 | 0.88 | LTA4H (0.56) | LTA4HESR2FAAH | |
| SCHEMBL5069931 | 0.88 | LTA4H (0.56) | LTA4HESR2FAAH | |
| Hydrochloric Acid SCHEMBL3597192 | 0.87 | LTA4H (0.55) | LTA4HESR2FAAH | |
| Hydrochloric Acid SCHEMBL3597194 | 0.87 | LTA4H (0.55) | LTA4HESR2FAAH | |
| Hydrochloric Acid SCHEMBL3598149 | 0.87 | LTA4H (0.55) | LTA4HESR2FAAH | |
| SCHEMBL3589105 | 0.84 | LTA4H (0.48) | LTA4HESR2FAAH | |
| SCHEMBL3589106 | 0.84 | LTA4H (0.48) | LTA4HESR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674802-B2 | leukotriene A4 hydrolase inhibitors; biaryl nitrogen-attached heterocycles | DECODE GENETICS, EHF (IS) | 2010-03-09 | — | — | US | disclosed |
| US-20070142434-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE CHEMISTRY, INC. (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142434-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | LTA4H, LTB4R, LTC4S | LTA4H 1/4885CASP3 1164/4885ESR2 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.