SCHEMBL359704

SCHEMBL359704

CCCC(C)(C)c1cc2c(c([N+](=O)[O-])c1)-c1c(cc([N+](=O)[O-])cc1[N+](=O)[O-])C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.49
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 3/20 0.34
GPR35 Q9HC97 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
HPRT1 P00492 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570302 0.84 HKDC1 (0.46) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL7522376 0.84 HKDC1 (0.56) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL74588 0.78 HKDC1 (0.65) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL29435119 0.78 HKDC1 (0.65) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL12396393 0.73 HKDC1 (0.59) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL8569104 0.70 HKDC1 (0.50) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL6541857 0.70 HKDC1 (0.56) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL3207925 0.70 HKDC1 (0.55) HKDC1ALDH1A1MAPTKDM4EMAPK1
SCHEMBL6378793 0.69 S100A4 (0.69) HKDC1ALDH1A1MAPTMAPK1TDP1
SCHEMBL11518981 0.69 S100A4 (0.61) HKDC1ALDH1A1MAPTMAPK1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060255322-A1 Methods and compositions for improved electrophoretic display performance WU ZARNG-ARH G 2006-11-16 US claimed
EP-1529242-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER Sipix Imaging, Inc. (US) 2005-05-11 EP claimed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US claimed
WO-2004010206-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER SIPIX IMAGING, INC. (US) 2004-01-29 WO claimed
US-8547628-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2013-10-01 US disclosed
US-8179589-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2012-05-15 US disclosed
US-20120013971-A1 METHODS AND COMPOSITIONS FOR IMPROVED ELECTROPHORETIC DISPLAY PERFORMANCE E INK CALIFORNIA, LLC 2012-01-19 US disclosed
US-20100301280-A1 METHODS AND COMPOSITIONS FOR IMPROVED ELECTROPHORETIC DISPLAY PERFORMANCE SIPIX IMAGING INC. 2010-12-02 US disclosed
US-7800813-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2010-09-21 US disclosed
US-7347957-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2008-03-25 US disclosed
US-20070152196-A1 METHODS AND COMPOSITIONS FOR IMPROVED ELECTROPHORETIC DISPLAY PERFORMANCE E INK CORPORATION 2007-07-05 US disclosed
US-20060255322-A1 Methods and compositions for improved electrophoretic display performance WU ZARNG-ARH G 2006-11-16 US disclosed
US-20050007648-A1 Methods and compositions for improved electrophoretic display performance E INK CORPORATION 2005-01-13 US disclosed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US disclosed