SCHEMBL3597209

SCHEMBL3597209

[NH]c1ccc2c(c1)NC(=O)C(CCO)O2

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.63
CYP3A4 P08684 1/20 0.48
TRPV1 Q8NER1 1/20 0.48
MAPK1 P28482 1/20 0.47
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 3/20 0.40
ALOX15 P16050 2/20 0.39
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3598938 0.89 L3MBTL1 (0.53) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL2101384 0.83 L3MBTL1 (0.63) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL7460746 0.83 L3MBTL1 (0.67) L3MBTL1USP2GAATSHRMEN1
SCHEMBL17055837 0.83 L3MBTL1 (0.63) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL7476434 0.83 L3MBTL1 (0.63) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL7468675 0.83 L3MBTL1 (0.63) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL18209180 0.83 L3MBTL1 (0.63) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL20414554 0.83 L3MBTL1 (0.63) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL13061281 0.81 L3MBTL1 (0.60) L3MBTL1CYP3A4TRPV1MAPK1USP2
SCHEMBL7468450 0.80 L3MBTL1 (0.62) L3MBTL1CYP3A4TRPV1MAPK1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100016285-A1 HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2010-01-21 US disclosed
EP-2128157-A1 HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2009-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016285-A1 HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE CCNY, CCND3, NSD3 L3MBTL1 1176/4885CYP3A4 621/4885TRPV1 2518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.