Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26311050 | 0.86 | L3MBTL1 (0.53) | L3MBTL1MAPK1USP2GAATP53 | |
| SCHEMBL7460746 | 0.83 | L3MBTL1 (0.67) | L3MBTL1USP2GAATSHRMEN1 | |
| SCHEMBL7476434 | 0.83 | L3MBTL1 (0.63) | L3MBTL1MAPK1CYP3A4TRPV1USP2 | |
| SCHEMBL17055837 | 0.83 | L3MBTL1 (0.63) | L3MBTL1MAPK1CYP3A4TRPV1USP2 | |
| SCHEMBL3597209 | 0.83 | L3MBTL1 (0.63) | L3MBTL1MAPK1CYP3A4TRPV1USP2 | |
| SCHEMBL7468675 | 0.83 | L3MBTL1 (0.63) | L3MBTL1MAPK1CYP3A4TRPV1USP2 | |
| SCHEMBL18209180 | 0.83 | L3MBTL1 (0.63) | L3MBTL1MAPK1CYP3A4TRPV1USP2 | |
| SCHEMBL2101384 | 0.83 | L3MBTL1 (0.63) | L3MBTL1MAPK1CYP3A4TRPV1USP2 | |
| SCHEMBL13061281 | 0.81 | L3MBTL1 (0.60) | L3MBTL1MAPK1CYP3A4TRPV1USP2 | |
| SCHEMBL7468450 | 0.80 | L3MBTL1 (0.62) | L3MBTL1MAPK1CYP3A4TRPV1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364237-B2 | Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease | LYCERA CORPORATION (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180208587-A1 | TETRAHYDROQUINOLINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE | LYCERA CORPORATION | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364237-B2 | Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease | RORA, RORC, RORB | L3MBTL1 4821/4885MAPK1 3728/4885CYP3A4 418/4885 |
| US-20180208587-A1 | TETRAHYDROQUINOLINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE | RORA, RORB, RORC | L3MBTL1 4725/4885MAPK1 3676/4885CYP3A4 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.