SCHEMBL3598938

SCHEMBL3598938

[NH]c1ccc2c(c1)OC(CCO)C(=O)N2

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 4/20 0.44
GAA P10253 2/20 0.44
BRD4 O60885 8/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
CYP3A4 P08684 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
MAPT P10636 2/20 0.39
MAPK1 P28482 1/20 0.39
CREBBP Q92793 2/20 0.37
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3597209 0.89 L3MBTL1 (0.63) L3MBTL1GAAKMT2AMEN1CYP3A4
SCHEMBL7465795 0.83 L3MBTL1 (0.56) L3MBTL1ALDH1A1GAABRD4KMT2A
SCHEMBL7466727 0.83 L3MBTL1 (0.53) L3MBTL1ALDH1A1GAABRD4KMT2A
SCHEMBL7460760 0.80 L3MBTL1 (0.53) L3MBTL1ALDH1A1GAABRD4KMT2A
SCHEMBL7476036 0.80 ALDH1A1 (0.67) L3MBTL1ALDH1A1GAABRD4KMT2A
SCHEMBL5670577 0.79 L3MBTL1 (0.58) L3MBTL1ALDH1A1GAAKMT2AMEN1
SCHEMBL20414554 0.74 L3MBTL1 (0.63) L3MBTL1GAAKMT2AMEN1CYP3A4
SCHEMBL7476434 0.74 L3MBTL1 (0.63) L3MBTL1GAAKMT2AMEN1CYP3A4
SCHEMBL18209180 0.74 L3MBTL1 (0.63) L3MBTL1ALDH1A1GAAKMT2AMEN1
SCHEMBL17055837 0.74 L3MBTL1 (0.63) L3MBTL1ALDH1A1GAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100016285-A1 HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2010-01-21 US disclosed
EP-2128157-A1 HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2009-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016285-A1 HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE CCNY, CCND3, NSD3 L3MBTL1 1176/4885ALDH1A1 1904/4885GAA 4641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.