Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592668 | 0.85 | KDM4E (0.47) | MAPK14ALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL3601237 | 0.83 | LMNA (0.45) | LMNAMAPK14ALDH1A1HPGDKDM4E | |
| SCHEMBL3598457 | 0.81 | MAPK14 (0.65) | MAPK14ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL3606513 | 0.77 | LMNA (0.45) | LMNAMAPK14ALDH1A1HPGDKDM4E | |
| SCHEMBL3605751 | 0.71 | SMN1; SMN2 (0.43) | LMNAMAPK14ALDH1A1HPGDKDM4E | |
| SCHEMBL13185669 | 0.69 | KDM4E (0.61) | LMNAALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL3613736 | 0.69 | MAPK14 (0.46) | LMNAMAPK14ALDH1A1HPGDKDM4E | |
| SCHEMBL29670209 | 0.68 | ALDH1A1 (0.68) | LMNAALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL3593014 | 0.68 | ALDH1A1 (0.68) | LMNAALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL3615683 | 0.68 | KDM4E (0.44) | LMNAALDH1A1HPGDKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
| WO-2006092059-A1 | DESIGN AND SYNTHESIS OF NOVEL ANTIMICROBIALS | WU FAN (CA) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | LMNA 743/4885MAPK14 3384/4885ALDH1A1 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.