Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allobarbital SCHEMBL35976 | 0.84 | LMNA (0.48) | MMP9LMNATP53 | |
| Allobarbital SCHEMBL11484021 | 0.82 | LMNA (0.46) | MMP9LMNATP53 | |
| Allobarbital SCHEMBL10817112 | 0.76 | MMP9 (0.41) | MMP9LMNATP53 | |
| Allobarbital SCHEMBL1887977 | 0.76 | LMNA (0.50) | MMP9LMNATP53KDM4E | |
| Etallobarbital SCHEMBL713588 | 0.73 | LMNA (0.64) | MMP9LMNATP53KDM4E | |
| SCHEMBL2048015 | 0.73 | MMP9 (0.42) | MMP9LMNATP53 | |
| SCHEMBL2048014 | 0.73 | MMP9 (0.42) | MMP9LMNATP53 | |
| SCHEMBL7646655 | 0.71 | MMP9 (0.41) | MMP9LMNATP53 | |
| SCHEMBL5065701 | 0.70 | ALDH1A1 (0.43) | MMP9LMNA | |
| SCHEMBL2051800 | 0.69 | MMP9 (0.36) | MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310216-B1 | Special 3-azabicyclo[3.1.0]hexanes, method for producing and modifying the same, and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |