Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.69 |
| ▸ | MMP12 | P39900 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | MMP13 | P45452 | 3/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | MMP7 | P09237 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.55 |
| ▸ | MMP14 | P50281 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446539 | 1.00 | MMP1 (0.69) | MMP1MMP12GAAMMP2MMP13 | |
| SCHEMBL359770 | 0.84 | MMP1 (0.79) | MMP1MMP12GAAMMP2MMP13 | |
| SCHEMBL4832364 | 0.83 | MMP1 (0.60) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL4832357 | 0.83 | MMP1 (0.60) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL29957946 | 0.83 | MMP1 (0.63) | MMP1MMP12GAAMMP2MMP13 | |
| SCHEMBL10890150 | 0.81 | MMP1 (1.00) | MMP1MMP12GAAMMP2MMP13 | |
| SCHEMBL25199019 | 0.79 | MEP1B (0.58) | MMP1MMP12GAAMMP2MMP13 | |
| SCHEMBL6802713 | 0.77 | MMP1 (0.69) | MMP1MMP12GAAMMP2MMP13 | |
| SCHEMBL8446048 | 0.77 | MMP1 (0.69) | MMP1MMP12GAAMMP2MMP13 | |
| SCHEMBL7827250 | 0.77 | LMNA (0.74) | GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |