SCHEMBL3600573

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13502999	0.92	TBK1 (0.51)	TBK1SIRT5CDK2CDK1CCNB1
	SCHEMBL3597064	0.86	PIK3CA (0.52)	CDK2MAPTNPC1XBP1MAPK1
	SCHEMBL3605169	0.85	CDK2 (0.51)	SIRT5CDK2MAPTNPC1XBP1
	SCHEMBL3596068	0.82	CDK2 (0.49)	SIRT5CDK2MAPTNPC1XBP1
	SCHEMBL3608406	0.81	CAMK2D (0.53)	SIRT5CDK2MAPTNPC1XBP1
	SCHEMBL3609046	0.80	CDK1 (0.65)	CDK2MAPTNPC1XBP1MAPK1
	SCHEMBL14140481	0.79	CAMK2D (0.49)	SIRT5CDK2MAPTNPC1XBP1
	SCHEMBL3602192	0.79	CAMK2D (0.58)	CDK2MAPTNPC1XBP1MAPK1
	SCHEMBL3606836	0.79	SYK (0.47)	SIRT5CDK2MAPTNPC1XBP1
	SCHEMBL3603147	0.78	CAMK2D (0.52)	SIRT5CDK2MAPTNPC1XBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.