Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.68 |
| ▸ | BACE1 | P56817 | 8/20 | 0.68 |
| ▸ | BCHE | P06276 | 5/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.59 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8055676 | 0.98 | ACHE (0.66) | ACHEBACE1BCHESIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL5862090 | 0.98 | ACHE (0.66) | ACHEBACE1BCHESIGMAR1KMT2A | |
| SCHEMBL4621350 | 0.94 | ACHE (0.60) | ACHEBACE1BCHESIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL27735117 | 0.92 | ACHE (0.59) | ACHEBACE1BCHESIGMAR1KMT2A | |
| SCHEMBL724604 | 0.90 | ACHE (0.69) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL242759 | 0.90 | ACHE (0.69) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL242760 | 0.90 | ACHE (0.69) | ACHEBACE1BCHESIGMAR1DRD4 | |
| Bromide SCHEMBL2497824 | 0.88 | ACHE (0.68) | ACHEBACE1BCHESIGMAR1DRD4 | |
| SCHEMBL13202835 | 0.86 | LTA4H (0.61) | ACHEBACE1BCHESIGMAR1KMT2A | |
| SCHEMBL31333800 | 0.84 | RECQL (0.56) | ACHEBACE1BCHESIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603285-A | Quercetin-3-O-glucuronide (1-benzyl-4-piperidinyl) methylamine compound and preparation method thereof | 江苏省林业科学研究院 | 2024-02-27 | — | — | CN | claimed |
| US-10669274-B2 | Azaphenalene-3-one derivative, preparation method therefor, and application therof | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-06-02 | — | — | US | claimed |
| US-20200031828-A1 | AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-01-30 | — | — | US | claimed |
| CN-106883232-B | A kind of derivative and the preparation method and application thereof of non-that alkene -3- ketone of azepine | 苏州康润医药有限公司 | 2019-01-22 | — | — | CN | claimed |
| US-20180099936-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-04-12 | — | — | US | claimed |
| CN-106883232-A | A kind of derivative of non-that ketone of alkene 3 of azepine and preparation method and application | 苏州康润医药有限公司 | 2017-06-23 | — | — | CN | claimed |
| EP-2780324-B1 | HETEROCYCLIC CARBOXAMIDES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE DEUTSCHLAND (DE) | 2017-05-17 | — | — | EP | claimed |
| US-20160318871-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE INC. | 2016-11-03 | — | — | US | claimed |
| US-20130116229-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE INC. (US) | 2013-05-09 | — | — | US | claimed |
| EP-0379145-B1 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID CO (US) | 1997-05-07 | — | — | EP | claimed |
| US-12240857-B2 | Adamantane derivatives for the treatment of filovirus infection | ARISAN THERAPEUTICS INC. (US) | 2025-03-04 | — | — | US | disclosed |
| CN-118894845-A | Apigenin derivative or solvate or pharmaceutically acceptable salt thereof and application thereof in preparation of uric acid reducing drugs | 江苏邦平科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115974723-B | Carboxamide ethylene anthracene compound, pharmaceutical composition containing same and application thereof | 中国药科大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-112638898-B | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117603285-A | Quercetin-3-O-glucuronide (1-benzyl-4-piperidinyl) methylamine compound and preparation method thereof | 江苏省林业科学研究院 | 2024-02-27 | — | — | CN | disclosed |
| CN-87100040-A | The alkylamine that alkyl diaryl replaces, its preparation technology's method, the medicine of using and containing this compounds | — | 1987-09-16 | — | — | CN | disclosed |
| EP-0229623-A2 | Diaryl-substituted alkylamines, procedure for their preparation, their application and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |
| US-4367232-A | ANOREXIGENIC AGENTS,ANESTHETICS | FORDONAL, S.A. (ES) | 1983-01-04 | — | — | US | disclosed |
| US-4289772-A | PHOSPHODIESTERASE INHIBITORS | PFIZER INC. (US) | 1981-09-15 | — | — | US | disclosed |
| US-3980788-A | XANTHENYL COMPOUNDS | SMITHKLINE CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240857-B2 | Adamantane derivatives for the treatment of filovirus infection | IFNAR1, MEP1B, MEP1A | ACHE 4710/4885BACE1 1266/4885BCHE 4637/4885 |
| US-20160318871-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | PDE3A, PDE5A, PDE3B | ACHE 60/4885BACE1 620/4885BCHE 595/4885 |
| US-20130116229-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | PDE7A, PDE5A, PDE2A | ACHE 34/4885BACE1 419/4885BCHE 404/4885 |
| US-20180099936-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | PDE3A, PDE5A, PDE3B | ACHE 59/4885BACE1 617/4885BCHE 593/4885 |
| US-20200031828-A1 | AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF | PARP1, PARP11, PARP8 | ACHE 4027/4885BACE1 1255/4885BCHE 3969/4885 |
| US-10669274-B2 | Azaphenalene-3-one derivative, preparation method therefor, and application therof | PARP1, PARP11, PARP8 | ACHE 4027/4885BACE1 1255/4885BCHE 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.