Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318016 | 0.78 | KMT2A (0.41) | MAPTL3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL841777 | 0.76 | RAB9A (0.59) | MAPTL3MBTL1KMT2ARAB9ANPC1 | |
| SCHEMBL2780925 | 0.75 | LMNA (0.42) | MAPTL3MBTL1ALDH1A1HTTLMNA | |
| SCHEMBL1594378 | 0.75 | LMNA (0.52) | MAPTCYP1A2RAB9ANPC1ALDH1A1 | |
| SCHEMBL4517477 | 0.75 | LMNA (0.42) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15993079 | 0.75 | KMT2A (0.38) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL21914125 | 0.75 | L3MBTL1 (0.43) | MAPTL3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL15993374 | 0.75 | L3MBTL1 (0.39) | MAPTL3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL366313 | 0.75 | RAB9A (0.40) | MAPTL3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL360533 | 0.74 | KMT2A (0.50) | MAPTL3MBTL1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12041933-B1 | N-(pyrimidin-2-ylcarbamothioyl) benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis (BOISD.) | King Faisal University (SA) | 2024-07-23 | — | — | US | claimed |
| US-12035715-B1 | 3,5-dinitro-n-(pyrimidin-2-ylcarbamothioyl)benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | King Faisal University (SA) | 2024-07-16 | — | — | US | claimed |
| CN-102838535-B | Preparation method of nicotinoyl thiourea derivatives | UNIV ZHEJIANG TECHNOLOGY | 2014-09-17 | — | — | CN | claimed |
| CN-102838535-A | Preparation method of nicotinoyl thiourea derivatives | UNIV ZHEJIANG TECHNOLOGY | 2012-12-26 | — | — | CN | claimed |
| CN-101851229-A | N-substituted pyridine acyl-N-substituted pyrimidyl thiourea derivant as well as preparation and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2010-10-06 | — | — | CN | claimed |
| EP-0039037-B1 | PYRIMIDYLTHIO-UREAS, MEDICINES CONTAINING THEM AND THEIR USE | Beiersdorf Aktiengesellschaft (DE) | 1985-01-16 | — | — | EP | claimed |
| EP-4629980-A1 | ANTIMICROBIAL COMPOUNDS | SRI International (US) | 2025-10-15 | — | — | EP | disclosed |
| CN-119930626-A | Preparation method of novel thiourea substance, antibacterial effect of composition and application of composition in aspect of promoting plant growth | 贵州工业职业技术学院 | 2025-05-06 | — | — | CN | disclosed |
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-118619952-A | Aloperine derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-10 | — | — | CN | disclosed |
| US-12041933-B1 | N-(pyrimidin-2-ylcarbamothioyl) benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis (BOISD.) | King Faisal University (SA) | 2024-07-23 | — | — | US | disclosed |
| US-12041933-B1 | N-(pyrimidin-2-ylcarbamothioyl) benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis (BOISD.) | King Faisal University (SA) | 2024-07-23 | — | — | US | disclosed |
| US-12035715-B1 | 3,5-dinitro-n-(pyrimidin-2-ylcarbamothioyl)benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | King Faisal University (SA) | 2024-07-16 | — | — | US | disclosed |
| EP-1218376-A4 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-20020147203-A1 | Tyrosine kinase inhibitors | MERCK & CO., INC. | 2002-10-10 | — | — | US | disclosed |
| EP-1218376-A1 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017995-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| EP-0039037-B1 | PYRIMIDYLTHIO-UREAS, MEDICINES CONTAINING THEM AND THEIR USE | Beiersdorf Aktiengesellschaft (DE) | 1985-01-16 | — | — | EP | disclosed |
| EP-0039037-A1 | Pyrimidylthio-ureas, medicines containing them and their use | Beiersdorf Aktiengesellschaft (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0039037-A1 | Pyrimidylthio-ureas, medicines containing them and their use | Beiersdorf Aktiengesellschaft (DE) | 1981-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147203-A1 | Tyrosine kinase inhibitors | ERBB2, TYRO3, TIE1 | MAPT 1182/4885L3MBTL1 2910/4885KMT2A 3298/4885 |
| US-12035715-B1 | 3,5-dinitro-n-(pyrimidin-2-ylcarbamothioyl)benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | DDT, NIT2, BRD8 | MAPT 4320/4885L3MBTL1 46/4885KMT2A 475/4885 |
| US-12041933-B1 | N-(pyrimidin-2-ylcarbamothioyl) benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis (BOISD.) | NIT2, BRD8, BRDT | MAPT 3819/4885L3MBTL1 28/4885KMT2A 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.