Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988247 | 0.78 | HSP90AA1 (0.36) | EPHX2 | |
| SCHEMBL13792027 | 0.78 | EPHX2 (0.41) | EPHX2 | |
| Benzimidazole SCHEMBL28428503 | 0.77 | ADORA2A (0.39) | HTTALDH1A1KDM4EMAPT | |
| SCHEMBL11038105 | 0.76 | SCN9A (0.46) | PLAUKDM4E | |
| SCHEMBL11023285 | 0.76 | AURKA (0.41) | LMNAPLAUALDH1A1KDM4EGAA | |
| SCHEMBL360111 | 0.75 | MAPT (0.52) | LMNAHTTALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6961244 | 0.75 | LMNA (0.52) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL1594378 | 0.75 | LMNA (0.52) | LMNAHTTALDH1A1KDM4EGAA | |
| SCHEMBL28991763 | 0.74 | L3MBTL1 (0.47) | LMNAKDM4EMAPTL3MBTL1 | |
| SCHEMBL5762582 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116422109-A | Self-extraction layered carbon dioxide trapping system and method | 嘉兴市碳捕手科技有限责任公司 | 2023-07-14 | — | — | CN | claimed |
| CN-101519378-B | Diaryl pyrimidyl guanidine and preparation method and pharmaceutical use of same | UNIV SHANXI NORMAL | 2011-07-20 | — | — | CN | claimed |
| CN-101519378-A | Diaryl pyrimidyl guanidine and preparation method and pharmaceutical use of same | UNIV SHANXI NORMAL | 2009-09-02 | — | — | CN | claimed |
| CN-220194438-U | Carbon dioxide trapping system with self-extraction layering function | 嘉兴市碳捕手科技有限责任公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-116422109-A | Self-extraction layered carbon dioxide trapping system and method | 嘉兴市碳捕手科技有限责任公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-3986465-A1 | SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften E. V. (DE) | 2022-04-27 | — | — | EP | disclosed |
| EP-3986466-A1 | SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften E. V. (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020254539-A1 | SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020254540-A1 | SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-12-24 | — | — | WO | disclosed |
| US-10414759-B2 | Phenylthiazoles and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180319784-A1 | PHENYLTHIAZOLES AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2018-11-08 | — | — | US | disclosed |
| EP-0062439-A1 | Guanidinopyrimidines | SMITHKLINE BECKMAN CORPORATION (US) | 1982-10-13 | — | — | EP | disclosed |
| EP-0062439-A1 | Guanidinopyrimidines | SMITHKLINE BECKMAN CORPORATION (US) | 1982-10-13 | — | — | EP | disclosed |
| EP-0062439-A1 | Guanidinopyrimidines | SMITHKLINE BECKMAN CORPORATION (US) | 1982-10-13 | — | — | EP | disclosed |
| EP-0061340-A1 | New pharmaceutical compositions containing guanidinopyrimidines | SMITHKLINE BECKMAN CORPORATION (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4347310-A | INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-08-31 | — | — | US | disclosed |
| US-4336254-A | Guanidinopyrimidine compounds, compositions and method of using as a diuretic | SMITHKLINE CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |
| US-4336254-A | Guanidinopyrimidine compounds, compositions and method of using as a diuretic | SMITHKLINE CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |
| US-4336254-A | Guanidinopyrimidine compounds, compositions and method of using as a diuretic | SMITHKLINE CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |
| US-4336255-A | DIURETICS | SMITHKLINE CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319784-A1 | PHENYLTHIAZOLES AND USES THEREOF | TPMT, TST, CLPP | LMNA 4725/4885HTT 2765/4885PLAU 169/4885 |
| US-10414759-B2 | Phenylthiazoles and uses thereof | TPMT, TST, CLPP | LMNA 4733/4885HTT 3052/4885PLAU 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.