Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334810 | 0.92 | L3MBTL1 (0.43) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL10918388 | 0.89 | PI4KB (0.42) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL10919161 | 0.87 | HDAC3 (0.40) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL10919157 | 0.87 | HDAC3 (0.40) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL4687185 | 0.87 | L3MBTL1 (0.50) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL2213116 | 0.87 | L3MBTL1 (0.62) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL17648650 | 0.85 | L3MBTL1 (0.45) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL3382178 | 0.85 | CYP1A2 (0.48) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL10915305 | 0.85 | L3MBTL1 (0.43) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL8983012 | 0.85 | MAPT (0.51) | L3MBTL1PI4KBHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | SPRING MILL PHARMA, INC. | 2024-08-15 | — | — | US | disclosed |
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| CN-101351457-A | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-01-21 | — | — | CN | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| EP-1963290-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| CN-101164618-A | A combination of fbpase inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2008-04-23 | — | — | CN | disclosed |
| CN-100352505-C | Combination of FBP enzyme inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | disclosed |
| WO-2007051560-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-10 | — | — | WO | disclosed |
| CN-1714866-A | A combination of fbpase inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2006-01-04 | — | — | CN | disclosed |
| CN-1350466-A | Combination of FBP enzyme inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2002-05-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | KCNB1, KCNA5, KCNA7 | L3MBTL1 637/4885PI4KB 1254/4885HDAC3 34/4885 |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | AADAC, HDHD5, HRH4 | L3MBTL1 220/4885PI4KB 3567/4885HDAC3 33/4885 |
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | L3MBTL1 455/4885PI4KB 1655/4885HDAC3 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.