Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601891 | 0.88 | GCK (0.57) | GCKMEN1KMT2AALDH1A1GAA | |
| SCHEMBL3603304 | 0.84 | NPC1 (0.68) | MEN1KMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL3596866 | 0.84 | MAPT (0.57) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3604622 | 0.83 | KDM4E (0.59) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL3597627 | 0.82 | SMN1; SMN2 (0.75) | GCKMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13156873 | 0.81 | NPC1 (0.74) | GCKMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8890163 | 0.81 | GRM5 (0.58) | GCKMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6799313 | 0.80 | RAB9A (0.60) | GCKMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4887357 | 0.80 | SMN1; SMN2 (0.55) | GCKL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31729501 | 0.80 | SMN1; SMN2 (0.63) | GCKMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| EP-1963290-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007051560-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | AADAC, HDHD5, HRH4 | GCK 1587/4885MEN1 3967/4885KMT2A 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.